摘要
植物生长调节剂(PGRs)与植物激素具有相似的生理作用和生物学效应,因而在农林业中应用越来越广泛。过度依赖PGRs促进植物生长所导致的农产品药物残留严重危害了人类的身体健康。研究证实,PGRs对人类及动物具有肝毒性、胰腺毒性、免疫毒性、遗传毒性和神经毒性,甚至致癌和致畸。另外,对人类和动物生殖系统也具有极大损害。本文集中讨论了PGRs可引发的各种毒性作用及相关机制的研究进展,并针对其损害雄性生殖系统健康的发生机制进行了归纳与总结,旨在引起人们对PGRs在食品或环境中的残留问题及安全问题的重视,最大限度降低PGRs对于人类健康的危害作用。
Plant growth regulators （PGRs） have similar physiological and biological effects to those of plant hormones, and therefore are used widely in agroforestry. The residues of PGRs in agricultural products are seriously detrimental to human health be- cause they have been found with hepatotoxicity, nephrotoxicity, genotoxicity, neurotoxicity, even carcinogenicity and teratogenicity. Furthermore, PGRs are suspected to disrupt the function of human and animal reproductive systems. This paper presents an overview on various toxicities of PGRs on human and animal reproductive health and their underlying mechanisms, aiming to arouse people＇s at- tention to PGR residues in food and environment and reduce PGR-induced damage to the male reproductive system and to human health as well.
作者
许春爽
姜宙
沈伟
邹淑花
XU Chun-shuang1;JIANG Zhou1;SHEN Wei1;2;ZOU Shu-hua1. 1. Center of Reproductive Medicine / Qingdao Laboratory for Assisted Reproduction and Germline Stem Cell Engineer- ing;Qingdao Women and Children＇s Hospital;Qingdao;Shandong 266034;China; 2. College of Life Sciences / Research Institute of Reproductive Science;Qingdao Agricultural University
出处
《中华男科学杂志》
CAS
CSCD
北大核心
2018年第4期370-375,共6页
National Journal of Andrology
基金
国家重点研发计划项目(2016YFD0501207)~~
关键词
植物生长调节剂
毒理学特征
雄性生殖
生殖毒理
plant growth regulator
toxicological characteristics
male reproduetivity
reproductive toxicology
