摘要
目的 评价血栓抽吸技术在对高血栓负荷的急性ST段抬高型心肌梗死（STEMI）行急诊经皮冠状动脉介入治疗（PPCI）中的作用.方法 将48例前降支为靶血管的STEMI患者采用随机数字表法分为对照组（常规支架植入）22例和观察组（血栓抽吸后再行支架植入）26例,比较两组术后心肌梗死溶栓试验血流分级（TIMI）、左心室射血分数值（LVEF）、血氨基末端脑钠肽（NT-ProBNP）值.结果 两组基线资料差异均无统计学意义（均P〉0.05）;观察组术后即刻血流TIMIⅢ级的占比明显高于对照组（26例比16例,χ2=4.810,P〈0.05）;观察组和对照组术后1周时LVEF值均较术后24 h时有所改善,但两者间差异均无统计学意义（t=1.803、1.796,均P〉0.05）;观察组术后7 d时的NT-ProBNP水平明显较对照组降低[（271.2±35.5）pg/mL比（806.5±65.8）pg/mL,t=3.154,P〈0.05].结论 血栓抽吸技术可明显减少高血栓负荷STEMI患者行PPCI时＂无复流＂的发生,改善心功能.
Objective To evaluate the effect of thrombus aspiration technique in emergency percutaneous coronary intervention for patients with ST segment elevation myocardial infarction （ STEMI ） .Methods According to the digital table ,48 patients with acute anterior myocardial infarction were randomly into 22 cases of control group （ routine stent implantation ） and 26 cases of observation group （ thrombus aspiration and then stent implantation ） .The changes of TIMI grading , left ventricular ejection fraction , NT -ProBNP were compared between the two groups . Results There were no significant differences in baseline data between the two groups （all P〉0.05）.The proportion of TIMI grade III of immediate blood flow in the observation group after operation was higher than that in the control group（26 cases vs.16 cases,χ2 =4.810,P〈0.05）.The LVEF values of the observation group and the control group at 1 week after operation were better than those after 24 h,but there was no statistically significant difference between the two groups （t=1.803,1.796,all P〉0.05）.The level of NT-ProBNP at 1 week after operation in the observation group was significantly lower than that in the control group [（271.2 ±35.5）pg/mL vs.（806.5 ±65.8）pg/mL,t=3.154,P〈0.05].Conclusion The thrombus aspiration technique can obviously reduce the occurrence of the ＂no reflow＂in STEMI patients with high thrombus load receive PPCI ,improve the heart function .
作者
朱建中
顾明
许浩军
汪强
谷惠敏
Zhu Jianzhong;Gu Ming;Xu Haojun;Wang Qiang;Gu Huimin(Department of Cardiology, the First People＇s Hospital of Kunshan , Kunshan , Jiangsu 215300, China)
出处
《中国基层医药》
CAS
2018年第4期409-412,共4页
Chinese Journal of Primary Medicine and Pharmacy
基金
江苏大学医学临床科技发展基金项目（JLY20120048）Medical Science and Technology Development Foundation of Jiangsu University
关键词
心肌梗死
血管成形术
气囊
冠状动脉
血栓栓塞
无复流现象
Myocardial Infarction
Angioplasty,Balloon,Coronary
Thromboembolism
No-Reflow Phenomenon
