摘要
目的通过动态监测上海市浦东新区孕妇尿碘水平变化,了解孕妇不同孕期的碘营养状况,为防治碘缺乏病工作提供依据。方法于2016年3—5月,采用整群随机抽样的方法,按照浦东新区地理区域划分在城区、城郊和郊区3个片区各抽取2个街镇,每个街镇随机抽30例孕早期孕妇,对自愿配合参与问卷调查并提供尿样的孕妇进行追踪调查。结果至分娩结束,共171例孕妇完成调查,其中城区57例、城郊55例和郊区59例,失访率为5.0%。孕早、中和晚期尿碘中位数分别为131.9μg/L、115.7μg/L和104.7μg/L,差异有统计学意义(P<0.05);孕早、中和晚期碘缺乏率分别为54.4%、64.9%和74.3%,差异有统计学意义(P<0.05);不同地理区域各孕期尿碘水平呈城区>城郊>郊区的趋势,其中孕早期和晚期的尿碘水平差异有统计学意义(P<0.05),孕中期的尿碘水平差异无统计学意义(P>0.05);不同年龄、文化程度、职业和盐碘摄入情况的孕妇各期尿碘水平比较差异无统计学意义(P>0.05)。结论浦东新区孕妇孕期内碘营养水平普遍不足,且随着孕期增加呈逐渐下降趋势。应进一步加强孕妇碘营养水平监测和评估,保障孕妇自身及胎儿的碘营养处于适宜范围。
[Objective]Through the dynamic monitoring on urinary iodine level of pregnant women in Pudong New Area of Shanghai,to understanding the iodine nutritional status of pregnant women in different periods,and provide the basis for the prevention and control of iodine deficiency disorders.[Methods]From March to May of 2016,by a cluster random sampling method,Pudong New Area was divided into three areas（urban district,rural-urban fringe zone and suburban district）according the geographical division,two sub-districts/towns were selected from each area,and 30 cases of early pregnancy women were collected from each sub-district/town.A follow-up survey was conducted in pregnant women who volunteered to participate in questionnaires and provide urine samples.[Results]At the end of childbirth,a total of 171 pregnant women completed the survey,including 57 cases from urban district,55 cases from rural-urban fringe zone and 59 cases from suburban district,and missing rate was 5.0%.Median urinary iodine concentration for the first,second and third trimester was respectively 131.9 μg/L,115.7 μg/L and 104.7 μg/L,and the difference was statistically significant（P 〈0.05）.The iodine deficiency rate for the first,second and third trimester was respectively 54.4%,64.9% and 74.3%,and the difference was statistically significant（P〈0.05）.The urinary iodine level in different geographical regions showed the trend of urban district 〉 rural-urban fringe zone 〉suburban district,and the differences in urinary iodine level in the first and third trimester were statistically significant among different geographical regions（P〈0.05）,while the difference in urinary iodine level in the second trimester was not statistically significant（P〉0.05）.There were no statistically significant differences in urinary iodine level among different groups in age,cultural level,occupation and salt iodine intake（P〉0.05）.[Conclusion]The iodine nutrition level of pregnant women in Pudong New Area is low,and it showed a downward trend with the increase of pregnancy period.It is necessary to further strengthen the monitoring and evaluation of iodine nutritional status of pregnant women,to ensure the iodine nutrition of pregnant women and their fetus in a suitable range.
作者
邬天凤
柏品清
任亚萍
沈惠平
胡燕
胡卉
WU Tian-feng;BAI Pin-qing;REN Ya-ping;SHEN Hui-ping;HU Yan;HU Hui(a Department of School,Nutrition and Food Hygiene, b Director＇s Office, c Physical and Chemical Laboratory, Center for Disease Control and Prevention of Pudong New Area,200136,China;Pudong Preventive Medicine Institute of Fudan University, Shanghai, 200136, China)
出处
《职业与健康》
CAS
2018年第5期617-621,共5页
Occupation and Health
基金
上海市浦东新区疾病预防控制中心卫生科技项目(PDCDC-2015-30)
关键词
孕妇
碘营养
尿碘
动态监测
Pregnant women
Iodine nutrition
Urinary iodine
Dynamic monitoring
