摘要
原发性肝癌是临床常见的恶性肿瘤,我国原发性肝癌的病死率位居肿瘤病死率的第3位。HBV/HCV感染和肝硬化等慢性肝病是原发性肝癌发生的重要危险因素,对于原发性肝癌的发生发展及预后均有一定影响。在原发性肝癌的治疗方面,肝切除术、肝移植、局部消融、肝动脉介入治疗、分子靶向治疗、化疗和放疗等在很大程度上提高了原发性肝癌患者的生存率,然而以上治疗均还存在一定的局限性。除了针对原发性肝癌本身的治疗,针对基础肝病的治疗在减少原发性肝癌的发生以及控制术后复发均有重要意义。对于基础肝病的治疗,首先要控制病因,如病毒感染者应进行抗病毒治疗等;同时也要进行控制炎症和纤维化的长期治疗。诸多研究证实,中医药在保肝抗炎及抗纤维化方面有其独特的优势,能够在原发性肝癌相关基础肝病的治疗中发挥有效作用。
Primary liver cancer is a common malignant tumor. In China, the fatality rate of primary liver cancerranks the third among cancers. Chronic liver diseases such as HBV/HCV infection and cirrhosis are importantrisk factors for primary liver cancer, which affect the development and prognosis. Currently, surgical treatmentssuch as liver resection and liver transplantation, local treatments such as local ablation and hepatic arteryinterventional therapy, and systemic treatments such as molecular targeted therapy and chemotherapy greatlyimprove the survival rate of patients with primary liver cancer. However, all these treatments have certainlimitations. In addition to the treatments for primary liver cancer, the treatment for basic liver disease is alsovery important, whether for reducing the occurrence of primary liver cancer or for controlling the recurrenceafter surgery. As for the treatment of basic liver diseases, the first thing to do is to control the causes. Forexample, patients with virus infection should be treated with antiviral therapy. A long-term treatment to controlthe inflammation and fibrosis is also needed. Plenty of studies have shown that traditional Chinese medicinehas a unique advantage in liver protection, anti-inflammatory and anti-fibrosis. Traditional Chinese medicineplays an effective role in the treatment of basic liver disease in patients with primary liver cancer.
作者
孙宁宁
孙凤霞
李晓玲
李杰
隋京利
SUN Ning-ning;SUN Feng-xia;LI Xiao-ling;LI Jie;SUI Jing-li(Department of Infectious Diseases,Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China;Department of Infectious Diseases, Shunyi Hospital of Beijing Hospital of Traditional Chinese Medicine,Beijing 101300, China)
出处
《中国肝脏病杂志（电子版）》
CAS
2018年第1期6-9,共4页
Chinese Journal of Liver Diseases：Electronic Version
基金
国家中医临床研究基地业务建设第二批科研专项课题(JDZX2015182)
北京中医医院院级课题暨两院合作课题(YJ-201736)
关键词
肝癌
原发性
基础肝病
治疗
中医药
Liver caner, primary
Basic liver disease
Treatment
Traditional Chinese medicine
