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脉冲染料激光抑制颌面部外伤早期瘢痕的效果评价 被引量:9

Effect of pulsed dye laser on inhibiting early scar after maxillofacial trauma
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摘要 目的:评价脉冲染料激光抑制颌面部外伤早期瘢痕的效果。方法:随机选取50例颌面部外伤术后患者,采用自身对照试验,将病灶平均分为治疗组和对照组。治疗组在拆线后即刻,拆线后15、30和60 d分别给予脉冲染料激光治疗,对照组不做治疗。采用皮肤数码显微镜拍摄治疗前和疗程结束后3个月治疗组和对照组瘢痕病灶照片并测量其面积,采用SPSS 13.0软件包对实验组和对照组病灶治疗前后面积差值进行统计学分析,由患者对病灶改善情况进行评分。结果:实验组37例患者达到治愈和显著改善,有效率位74%;对照组11例患者显著改善,有效率位22%。实验组和对照组治疗前、后瘢痕面积差值具有显著差异(P<0.05),患者平均满意度较高。未见明显不良反应。结论:脉冲染料激光在抑制颌面部外伤早期瘢痕中疗效确切,为减少颌面部外伤早期瘢痕提供了安全可靠的方法。 PURPOSE: The study was designed to explore an effective method to control early scar after maxillofacial trauma and improve the satisfaction of clinical treatment. METHODS: Fifty skin lesions after maxillofacial trauma were divided into the experimental group and control group. Patients in the experimental group were treated with pulsed dye laser when taking out stitches, 15, 30 and 60 days later. Digital microscope photos were taken and lesion area was measured before and 3 months after laser irradiation. Adverse effects were recorded during and after each treatment as well. All patients were asked to rate their satisfaction at 3-month of follow-up. Statistical analysis was performed using SPSS 13.0 software package. RESULTS: The efficiency of the experimental group was 74% and 37 lesions were cured or significantly improved, while the efficiency rate was 22% in the control group. Area reduction of maxillofacial lesions before and after treatment between the two groups was significantly different(P〈0.05). Patients in the experimental group were highly satisfied with the final outcomes. No severe adverse events were observed. CONCLUSIONS: Pulsed dye laser is safe and effective in inhibiting early scar following maxillofacial trauma.
作者 董依云 陶岚 周国瑜 王海宁 朱亚琴 DONG Yi-yun;TAO Lan;ZHOU Guo-yu;WANG Hai-ning;ZHU Ya-qin(Department of General Dentistry;Deportment of Oromaxillofacial Head and Neck Oncalogy, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center of Stomatology, Shanghai Key Laboratory of Stomatology and Shanghai Research Institute of Stomatology. Shanghai 200011, China)
出处 《上海口腔医学》 CAS CSCD 北大核心 2018年第2期200-203,共4页 Shanghai Journal of Stomatology
关键词 脉冲染料激光 颌面部外伤 早期瘢痕 Pulsed dye laser Maxillofacial trauma Early scar
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