摘要
三阴性乳腺癌尚无统一的诊治标准,内分泌药物及针对HER-2的靶点诊治效果均不佳,化疗效果也不尽如人意。三阴性乳腺癌侵袭转移能力强,邪毒炽盛一直占据着病机的主要地位。因此,以散结解毒为代表的祛邪法应贯穿于整个治疗过程中,同时兼顾扶正固本。蛇六谷辛寒,有毒,归肝脾经,有化痰、行瘀、散结、消肿、解毒等功效,其治疗三阴性乳腺癌的效果已在临床和实验研究中得到证实,但仍需进行深入的临床与基础研究,寻找相关蛋白、基因组学等方面的证据及蛇六谷抑制瘤体生长的具体起效靶点等。
There is no uniform diagnosis and treatment criteria for triple-negative breast cancer,and the effects of endocrine drugs and targets targeting HER-2 are poor,and the effect of chemotherapy is not satisfactory. The ability of triple-negative breast cancer to invade and metastasize is strong,and the exuberant of cult poison has always occupied the main position of the pathogenesis,therefore,the exorcism which represented by removing stasis and detoxification should be carried throughout the entire course of treatment,and at the same time,strengthening body resistance must be taken into account. Sheliugu＇ s traites are spicy,cold and poisonous,the meridian belongs to liver and spleen. It has many effects,for example,exclude sputum,promote the blood stasis,remove stasis,eliminate swelling and detoxification. It＇s effect of treating triple negative breast cancer has been confirmed in clinical and experimental studies. But still need to conduct in-depth clinical and basic research,search for evidence on related proteins,genomics,etc.,and the specific target of inhibiting the growth of tumors.
作者
邓丹丹
潘立群
DENG Dandan;PAN Liqun(Mengcheng Traditional Chinese Medicine Hospital, Mengcheng Anhui China 233500;Nanjing University of Chinese Medicine, Nanjing Jiangsu China 210029)
出处
《中医学报》
CAS
2018年第4期541-544,共4页
Acta Chinese Medicine
关键词
三阴性乳腺癌
肿瘤
蛇六谷
中医药治疗
triple-negative breast cancer
tumor
Sheliugu （ Rhizoma Amorphophalli）
TCM therapy
