摘要
目的观察局部晚期宫颈癌患者运用调强放疗联合腔内照射治疗的临床疗效。方法选取我院2016年11月至2017年11月期间诊治的32例局部晚期宫颈癌患者作为研究对象,所有患者均行调强放疗联合腔内照射治疗,观察其治疗效果、副毒作用以及生存情况。结果临床疗效评价中,完全缓解24例,部分缓解6例,稳定2例,有效率为93.8%;副毒作用中,出现胃肠道反应6例,骨髓抑制反应6例,皮肤、黏膜反应32例,泌尿系统反应2例,均为急性;生存情况中,4例死亡,死亡率为12.5%,1年总生存率为100%(32/32),2年总生存率为90.6%(29/32),1年无病生存率为93.8%(30/32),2年无病生存率为87.5%(28/32)。结论局部晚期宫颈癌患者运用调强放疗联合腔内照射治疗的临床疗效显著,生存率较高,值得临床应用。
Objective To observe clinical effect of intensity modulated radiotherapy combined with intracavitary irradiation for local advanced cervical cancer patients. Methods Choose 32 cases local advanced cervical cancer patients treated in our hospital from November 2016 to November 2017 as research subjects. Treat them with intensity modulated radiation therapy combined with intracavitary irradiation, observe curative effects, side effects and survival condition. Results For clinical evaluation, 24 cases were totally relieved, 6 cases partially relieved, 2 cases were stable, effective rate was 93.8%; for side effects, 6 cases had gastrointestinal reaction, 6 cases bone marrow inhibition, 32 cases skin and mucosa reaction, 2 cases urinary tract reaction, all of them were acute; for survival situation, 4 cases died with mortality rate of 12.5%, 1 year survival rate was 100%（32/32）, total survival rate of 2 years was 90.6%（29/32）, 1 year disease-free survival rate was 93.8%（30/32）, 2-year disease-free survival rate was 87.5%（28/32）. Conclusion Intensity modulated radiotherapy combined with intracavitary irradiation has remarkable curative effect for local advanced cervical cancer patients, with high clinical survival rate, which is worthy of clinical practice.
作者
朱永法
张传楣
ZHU Yong-fa;ZHANG Chuan-mei(Changyi City People＇s Hospital of Shandong, Shandong, Changyi, 261300)
出处
《智慧健康》
2018年第3期22-23,共2页
Smart Healthcare
关键词
局部晚期宫颈癌
调强放疗
腔内照射
Local advanced cervical cancer
Intensity modulated radiotherapy
Intracavitary irradiation
