摘要
目的探讨亚临床甲状腺功能障碍与颈动脉斑块发生风险因素之间的关系。方法对郑州大学第一附属医院健康检查中心2012年1月至2016年12月期间进行甲状腺功能检测(TFTs)和颈动脉超声检查中具有亚临床甲状腺功能障碍的患者进行分析,并运用多种统计学方法研究亚临床甲状腺功能障碍与颈动脉斑块之间的关系。结果颈动脉斑块在亚临床甲状腺功能减退患者中更为常见(52.8%)。但多因素分析显示,甲状腺功能状态与患颈动脉斑块的风险无关,而在亚临床甲状腺功能减退的患者中,传统的脑血管危险因素如年龄、收缩压、空腹血糖和肌酐与颈动脉斑块相关。结论亚临床甲状腺功能障碍不影响健康人颈动脉斑块的发展。
Objective To explore the relationship between subclinical thyroid dysfunction and risk of carotid atherosclerosis. Methods To analyze the patients with thyroid function tests （ TFTs ） and carotid artery-duplex ultrasonography in the Department of Health Screening Center of the First Affiliated Hospital of Zhengzhou Universityfrom January of 2012 to December of 2016, and to use a variety of statistical methods to study the relationship of subclinical thyroid dysfunction and carotid arteryplaque. Results Carotid plaques were more common in the subclinical hypothyroidism （52. 2% ） than the euthyroidism （47. 8% ） at baseline. However, in multivariable analysis, thyroid status was not a significant risk for the carotid plaques at baseline. Traditional cerebrovascular risk factors such as age, systolic blood pressure, fasting blood glucose, and creatinine were associated with baseline carotid plaques in subclinical hypothyroidism. Conclusion Subclinical thyroid dysfunction do not affect the development of carotid plaques.
作者
杨娟
魏振玲
Yang Juan;Wei Zhenling(The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Chin)
出处
《河南医学研究》
CAS
2018年第9期1540-1542,共3页
Henan Medical Research
基金
国家自然科学基金资助项目(81701553)
关键词
亚临床甲状腺功能障碍
颈动脉斑块
脑血管
危险因素
subclinical thyroid dysfunction
carotid atherosele-rosis
cerebrovaseular
risk factors
