摘要
为探讨生长抑素联合介入性动脉灌注化疗治疗恶性肠梗阻的临床效果,将符合纳入标准的60例恶性肠梗阻患者按入院先后顺序随机分为A、B、C 3组,各20例。3组均接受常规治疗,在此基础上,A组接受生长抑素静脉给药,B组接受介入性动脉灌注化疗,C组同时接受生长抑素静脉给药和介入性动脉灌注化疗。对比3组患者胃肠减压量、症状缓解时间、症状缓解持续时间。结果显示,1)胃肠减压量:A组和C组胃肠减压量均明显少于B组,P<0.05;A组与C组比较差异无统计学意义,P>0.05。2)症状缓解时间:A组和C组症状缓解时间明显短于B组,P<0.05;A组与C组比较差异无统计学意义,P>0.05。3)症状缓解持续时间:B组和C组症状缓解持续时间明显长于A组,P<0.05;B组和C组比较差异无统计学意义,P>0.05。结果表明,生长抑素可以明显减少胃肠减压量,快速缓解肠梗阻所造成的临床症状;介入性动脉灌注化疗可提高症状缓解的维持时间;生长抑素联合介入性动脉灌注化疗治疗恶性肠梗阻,症状缓解更快,持续时间更长,效果更好。
This study was to explore the clinical effect of somatostatin plus interventional irrigation chemotherapy via artery in the treatment of malignant bowel obstruction,randomly divided 60 cases of this disease met enrolled standard into group A,B,and C according to admitted sequency,20 cases for each,which the three groups were all received routine therapies, then group A was added intravenously administering somatostatin,group B received interventional artery-approach irrigation chemotherapy, group C received the combination of two therapies used in group A and B; then compared the following indexes as patient＇s gastro-intestinal decreased pressure, relief time of symptoms and its lasting duration between the three groups.As results, 1）gastro-intestinal decreased pressure： compared with group B,A and C were all signifi- cantly less （ P 〈0.05） ,but there was no statistical difference between group A and group C（ P 〉0.05） ;2） relief time of symptoms：compared with group B,group A and C were all significantly shorter（ P 〈0.05）, but there was no statistical difference between group A and group C（ P 〈0.05）;3）the lasting duration of relief time of symptoms：compared with group A,group B and C were significantly longer（ P 〉0.05） ,but there was no statistical difference between group B and group C（ P 〉0.05）.Results show that somatostatin may decrease gastro-intestinal decreased pressure, thus fastly relieve symptoms induced by obstruction;interventional irrigation chemotherapy via artery may increase lasting duration of symptom＇s relief,therefore both in the treatment of malignant intestinal obstruction make symptom faster relieved, lasting duration longer, effect better.
作者
靳金龙
JIN Jin-long(Dept. of Intervention for Peripheral Vascular Diseases, Gansu Provincial Hospital of TCM , Lanzhou , Gansu 73050)
出处
《中国肛肠病杂志》
2018年第2期11-13,共3页
Chinese Journal of Coloproctology
关键词
恶性肠梗阻
生长抑素
介入性动脉灌注
化疗
效果
Malignant intestinal obstruction
Somatostatin
Interventional artery irrigation
Chemotherapy
Efficacy
