摘要
颅脑外伤后脑积水是颅脑外伤,尤其是严重颅脑外伤后常见的继发性损害,常常导致严重的脑组织代谢紊乱和功能障碍,影响颅脑外伤患者的康复过程,增加致残率。颅脑外伤继发脑积水的发病机制与脑脊液循环通路的阻塞相关,而脑脊液循环通路的纤维化在其发生机制中亦占有重要地位。脑积水发生的相关危险因素对于患者的预防和治疗具有重要意义。因此,提高对颅脑外伤后脑积水发生、发病机制及相关危险因素的认识,可以早期诊断颅脑外伤后脑积水,降低致残率及病死率。
The hydrocephalus after craniocerebral trauma is a common secondary injury of the craniocerebral trauma,especially severe craniocerebral trauma. It often leads to severe metabolic disorders and dysfunction of the brain tissue,which affects the recovery process of craniocerebral trauma patients and increases the rate of disability. The pathogenesis of post-traumatic hydrocephalus is related to the obstruction of cerebrospinal fluid circulation pathway,and the fibrosis of cerebrospinal fluid circulation pathway plays an important role in its pathogenesis. The related risk factors of hydrocephalus are of great significance for the prevention and treatment. Therefore,to improve the understanding of its occurrence,pathogenesis and related risk factors,is helpful to the early diagnosis to reduce the disability and mortality rate of the patients.
作者
孙硕
周辉
施辉
SUN Shuo;ZHOU Hui;SHI Hui(Department of Neurosurgery ,Xuzhou Medical University Affiliated Lianyungang Hospital, Lianyungang 222000, Chin)
出处
《医学综述》
2018年第9期1739-1742,1748,共5页
Medical Recapitulate
基金
江苏省"六大人才高峰"高层次人才选拔培养资助(WSW-166)
关键词
颅脑外伤
脑积水
危险因素
创伤后脑积水
创伤性脑损伤
Craniocerebral trauma
Hydrocephalus
Risk factors
Post-traumatic hydrocephalus
Traumaticbrain injuries
