摘要
目的观察、分析在双向情感患者的治疗中,总结并阐述喹硫平与丙戊酸钠治疗法对治疗双向情感性精神障碍狂躁发作的治疗效果。方法特选取双向情感患者120例作为研究对象;分为两组。每组60例,对照组应用丙戊酸钠治疗路径;实验组应用喹硫平治疗路径。观察分析两组的治疗效果。结果与治疗前相比,在治疗的5周时间内两组狂躁量表评分均有明显的降低趋势,实验组治疗随着时间的增长每周的检测评分明显降低(P<0.05),对照组除了第1周降低不是很明显,另外3周评分也随着时间的增长显著降低(P<0.05),两组降低趋势对比差异无统计学意义;经过5周治疗,实验组治疗有效率到96.7%,对照组治疗有效率达到95.0%,两组差异无统计学意义。结论在双向情感患者的治疗中,相比于应用丙戊酸钠治疗路径来说,喹硫平治疗路径的治疗不良反应少,安全性高,值得应用。
Objective To observe and analyze the therapeutic effect of quetiapine and valproate on the treatment of bipolar disorder in the treatment of bipolar affective disorder. Methods 120 patients were selected as the study subjects. There are two groups. 60 patients in each group were treated with valproate. The experimental group applied quetiapine treatment pathway. Observe and analyze the therapeutic effect of the two groups.Results Compared with before treatment, the treatment of two groups of 5 weeks time mania scores were significantly lower trend, experimental treatment as the growth of the time weekly test scores significantly decreased（P〈0.05）, the control group in addition to the first week to reduce is not very obvious, the other 3 weeks score as the growth of the time also significantly reduced（P〈0.05）, no difference between the two groups was decreased contrast; After 5 weeks of treatment, the treatment rate of the experimental group was 96.7%, and the effective rate of the control group was 95.0%, and the difference between the two groups was not significant. Conclusion In the treatment of patients with bipolar disorder, the treatment pathway of quetiapine is less effective and safe than the treatment of valproate.
作者
彭国胜
Peng Guosheng(Fuzhou Third Hospital,Fuzhou,Jiangxi, 344000,Chin)
出处
《当代医学》
2018年第15期105-106,共2页
Contemporary Medicine
