摘要
近年贫血或铁缺乏对心力衰竭预后的影响引起广泛关注。贫血或铁缺乏在心力衰竭中的患病率及发病率较高,贫血或铁缺乏可能与心力衰竭预后独立相关。心力衰竭发生贫血或缺铁的因素主要有合并慢性肾脏疾病、胃肠道淤血、慢性炎症、血液稀释、合并糖尿病、口服药物影响等,可通过多种检验指标明确心力衰竭合并贫血或缺铁,如血红蛋白、血清铁、血清铁蛋白、转铁蛋白饱和度、可溶性转铁蛋白受体、红细胞分布宽度、红细胞生成素等。临床上治疗心力衰竭合并贫血或缺铁方案主要有口服补铁,静脉补铁,促红细胞生成素及联合治疗,选择恰当治疗方案利于改善心力衰竭预后。现将从心力衰竭合并贫血或铁缺乏的患病率、作用机制、诊断标准、化验指标及治疗加以阐述。
In recent years,anemia or iron deficiency on the prognosis of heart failure has caused widespread concern. The prevalence and incidence of anemia or iron deficiency in heart failure is high, but may be independent with the prognosis od heart failure. Heart failure, anemia or iron deficiency factors are mainly combined with chronic kidney disease, gastrointestinal congestion, chronic inflammation, blood dilution, diabetes and oral drug effects. A variety of test indicators make clear heart failure with anemia or iron deficiency,such as hemoglobin, serum iron,serum ferritin, transferrin saturation, soluble transferrin receptor, erythrocyte distribution width and erythropoietin. Clinical treatment of heart failure with anemia or iron deficiency are mainly oral iron,intravenous iron,erythropoietin and combination therapy. An appropriate treatment program will help to improve the prognosis of heart failure. This review will describe the prevalence,mechanism of action, diagnostic criteria, laboratory markers and treatment of heart failure associated with anemia or iron deficiency.
作者
袁丽君
孔一慧
YUAN Lijun;KONG Yihui(Harbin Medical University Graduate School,Harbin 150000,Heilongjiang,China;Department of Cardiology,The First Affiliated Hospital of Harbin Medical University,Harbin 150000,Heilongjiang,China)
出处
《心血管病学进展》
CAS
2018年第3期402-407,共6页
Advances in Cardiovascular Diseases
关键词
心力衰竭
贫血
铁缺乏
化验指标
贫血治疗
Heart failure
Anemia
Iron deficiency
Laboratory indicators
Anemia treatment
