摘要
目的:评价0.1%他克莫司软膏治疗阴囊慢性湿疹的临床效果和安全性。方法:采用随机对照法将57例患者分为两组,治疗组29例,给予0.1%他克莫司软膏外涂,每日早晚各一次;对照组28例,给予青鹏软膏外涂,用法同治疗组,疗程均为4周,于治疗第2周和第4周比较两组治疗效果,并记录不良反应。结果:治疗组治疗第2周和第4周的有效率优于对照组,差异有统计学意义(P<0.05)。治疗组药物不良反应主要表现为用药部位烧灼感和瘙痒,均可耐受,且为一过性。结论:0.1%他克莫司软膏治疗阴囊慢性湿疹具有良好的效果,安全性高。
Objective：To evaluate the clinical effect and safety of 0.1% Tacrolimus Ointment for chronic eczema of scrotum.Method：Total of 57 patients with chronic eczema of scrotum were divided into the treatment group and the control group according to random control method.29 cases in the treatment group received external application of 0.1% Tacrolimus Ointment,twice a day.28 cases in the control group received external application of Qingpeng Ointment and the usage was the same as the treatment group.The course of treatment was four weeks for both groups.The efficacy of two groups after treatment was compared and the adverse reactions were recorded.Result：The effective rate in the treatment group were higher than those in the control group,after treatment of 2 weeks and 4 weeks,there were statistical differences between the groups（P0.05）.Drug related adverse reactions of the treatment group were mainly manifested as burning sensation and pruritus,which were both tolerable and transient.Conclusion：0.1% Tacrolimus Ointment is effective and safe for the treatment of chronic eczema of scrotum.
作者
张翠松
ZHANG Cuisong(Mentougou District Hospital of Beijing City,Beijing 102300,China)
出处
《中外医学研究》
2018年第14期130-132,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
慢性湿疹
阴囊
他克莫司软膏
Chronic eczema
Scrotum
Tacrolimus ointmen
