摘要
延龄草皂苷是从延龄草属植物中提取分离的甾体皂苷,是发挥生物活性作用的主要成分。其通过抑制肿瘤细胞增殖,诱导肿瘤细胞凋亡,抑制肿瘤细胞转移,逆转耐药性,调节机体免疫力,增强化疗药物疗效等发挥抗肿瘤的作用。本综述主要分析和总结延龄草皂苷抗肿瘤作用的主要途径和机制。
Trillium saponin is a steroidal saponin extracted from the genus Trillium, which is the main component playing biological activity. It plays an anti-tumor effect by inhibiting tumor cell proliferation, inducing tumor cell apoptosis, inhibiting tumor cell metastasis, reversing drug resistance, regulating immunity, enhancing the efficacy of chemotherapy drugs. This review has analyzed and summarized the main pathways of the anti-tumor effect of Trillium saponins.
作者
王金龄
喻玲玲
邓晓卓
刘习建
陈静文
WANG Jinling;YU Lingling;DENG Xiaozhuo;LIU Xijian;CHEN Jingwen(Medical College of Three Gorges University, Yichang 443002, Chin)
出处
《生命的化学》
CAS
CSCD
2018年第2期224-228,共5页
Chemistry of Life
基金
国家自然科学基金项目(1215181)
关键词
延龄草皂苷
抗肿瘤
作用机制
Trillium saponins
antitumor
mechanism of action
