摘要
目的探究胃镜钛夹止血联合肾上腺素注射对非静脉曲张上消化道出血临床疗效以及对不良事件、生活质量的影响。方法选取2016年4月~2017年4月收治的86例非静脉曲张上消化道出血患者临床资料进行分析,将行胃镜注射肾上腺素治疗者作为对照组(43例),行胃镜钛夹止血与肾上腺素注射联合治疗者作为研究组(43例),比较两组止血效果、不良事件发生率、生活质量评分情况。结果研究组及时止血与有效止血率分别为97.67%、90.69%,均较对照组高,差异比较具统计学意义(P<0.05),研究组再出血率2.32%显著低于对照组(P<0.05);研究组不良事件总发生率9.30%较对照组显著低,比较差异具有统计学意义(P<0.05);研究组SF-36躯体疼痛(78.91±5.02)分、活力(80.12±5.04)分、心理职能(82.34±5.16)分、社会职能(81.55±5.22)分均高于对照组,比较差异具有统计学意义(P<0.05)。结论非静脉曲张上消化道出血患者联合肾上腺素注射与胃镜钛夹止血,能够有效提升止血效果,减少不良事件的发生,从而促进生活质量改善,具推广及应用价值。
Objective To explore the clinical efficacy of endoscopic titanium clip hemostasis combined with epinephrine injection in the treatment of non-variceal upper gastrointestinal bleeding and its effects on adverse events and quality of life. Methods The clinical data of 86 patients with non-variceal upper gastrointestinal bleeding who had been seeking treatment in the hospital between April 2016 and April 2017 were selected for analysis. The patients given endoscopic epinephrine injection were taken as the control group（n=43）, whereas those given endoscopic titanium clip hemostasis combined with epinephrine injection as the study group（n=43）. The hemostatic effect, incidence of adverse events and scores of life quality were compared between the two groups. Results The timely and effective bleeding control rates in the study group were 97.67% and 90.69%respectively, both higher than the control group, the differences were statistically significant（P〈0.05）; the rebleeding rate in the study group was2.32%, significantly lower than the control group（P〈0.05）; the total incidence of adverse events in the study group was 9.30%, significantly lower than the control group, the difference was statistically significant（P〈0.05）; the SF-36 scores of physical pains was（78.91±5.02） in the study group,vitality was（80.12±5.04）, psychological function（82.34±5.16）, and social function was（81.55±5.22）, all shown to be higher than the control group,the differences were statistically significant（P〈0.05）. Conclusion For patients with non-variceal upper gastrointestinal bleeding, epinephrine injection combined with endoscopic titanium clip hemostasis can effectively improve the hemostatic effect, reduce the incidence of adverse events, so as to improve their quality of life; it is of significant value to be popularized in clinical application.
作者
韦春秋
蒙爱明
潘素华
何建生
Wei Chunqiu;Meng Aiming;Pan Suhua;He Jiansheng(Department of Gastroenterology,People＇s Hospital of Laibin City,Laibin,Guangxi,546100,China)
出处
《当代医学》
2018年第16期89-92,共4页
Contemporary Medicine
关键词
胃镜钛夹止血
非静脉曲张上消化道出血
肾上腺素注射
不良事件
生活质量
Endoscopic Titanium Clip Hemostasis
Non-variceal Upper Gastrointestinal Bleeding
Epinephrine Injection
Adverse Events
Quality of Life
