摘要
目的 :比较使用抗甲状腺药物(ATD)与碘131治疗甲状腺功能亢进症(甲亢)的效果。方法 :选取2015年6月至2016年7月期间彭州市中医医院收治的110例甲亢患者作为研究对象。随机将这些患者分为对照组(55例)和治疗组(55例)。为对照组患者使用ATD(丙硫氧嘧啶和甲巯咪唑)进行治疗。为治疗组患者使用碘131进行治疗。然后观察两组患者三碘甲状原氨酸(T3)、血清甲状腺素(T4)、游离三碘甲状原氨酸(FT3)、游离甲状腺素(FT4)及促甲状腺激素(TSH)的水平,统计其不良反应的发生率及病情的复发率。结果:治疗后,治疗组患者T3的水平、T4的水平、FT3的水平、FT4的水平、不良反应的发生率及病情的复发率均低于对照组患者(P<0.05),其TSH的水平高于对照组患者(P<0.05)。结论 :与使用ATD相比,使用碘131治疗甲亢可有效地控制其血清甲状腺激素的水平,降低其病情的复发率,且安全性更高。
Objective： To compare effects between antithyroid drug and Iodine 131 for hyperthyroidism. Methods： 110 patients with hyperthyroidism admitted to Traditional Chinese Medicine Hospital of Pengzhou City during June 2015 to July 2016 were enrolled for research object. Randomly divide the patients to control group（55 cases）and experimental group（55 cases）. Treat control group with ATD（propylthiouracilum and methimazole）,treat experimental group with Iodine 131.Then observe levels of T3,T4,FT3,FT4 TSH of 2 groups, and count up occurrence of adverse reaction and recurrence rate of 2 groups. Results： After treatment, levels of T3,T4,FT3,FT4 of experimental group are lower than that in control group（P〈 0.05）,level of TSH of experimental group is higher than that in control group（P 〈0.05）. Conclusion： Compare with ATD,treat hyperthyroidism with Iodine 131 will control thyroid hormones of patients effectively, decrease recurrence rate, and safety is high.
作者
刘兴杨
LIU xingyang(Department of nuclear medicine, Traditional Chinese Medicine Hospital of Pengzhou City Sichuan Chengdu 611930)
