摘要
以甲苯为底物,醋酸钴为催化剂,溴化钠为引发剂,过氧乙酸为液相氧化剂,在脉冲型微通道反应器中液相氧化合成苯甲醛,考察了原料配比、停留时间、反应温度、催化剂、引发剂用量和溶剂量等工艺参数对合成反应的影响。结果表明,n(甲苯)∶n(过氧乙酸)=1∶3、V(甲苯)∶V(乙酸)=1∶5、n(乙酸钴)∶n(甲苯)=1∶75、n(溴化钠)∶n(甲苯)=1∶30、反应温度为110℃、停留时间为10 min时,甲苯转化率达到30.8%,苯甲醛选择性达到83.5%。与传统间歇反应工艺相比,微通道反应器通过对反应过程中传质传热的强化,可大幅提高反应速率及原料的利用率,扩大工艺条件选择区间,实现对氧化反应过程的有效控制。
Benzaldehyde is synthesized through liquid-phase oxidation method in a pulsed microchannel reactor with toluene as substrate,cobalt acetate as catalyst,sodium bromide as initiator and peracetic acid as liquid phase oxidant.The effects of raw materials ratio,residence time,reaction temperature,adding amount of catalyst and initiator and solvent amount on the reaction are investigated. The results show that the conversion rate of toluene can reach 30. 8% and the selectivity of benzaldehyde can be 83. 5% when n(toluene） ∶ n(peroxyacetic acid） = 1 ∶3,V(toluene） ∶ V(acetic acid） =1 ∶5,n(cobalt acetate） ∶ n(toluene） = 1 ∶75,n(sodium bromide） ∶ n(toluene） = 1 ∶30,the reaction temperature remains at 110℃ and the residence time is 10 min. Compared with the traditional batch reaction process,the microchannel reactor can strengthen mass transfer and heat transfer during the reaction process,which can greatly enhance the reaction rate and the utilization rate of raw materials,expand the selection range of process conditions and realize effective control on the oxidation reaction process.
作者
张跃
张勇超
严生虎
刘建武
沈介发
陈代祥
沈禹凡
ZHANG Yue;ZHANG Yong-chao;YAN Sheng-hu;LIU Jian-wu;SHEN Jie-fa;CHEN Dai-xiang;SHEN Yu-fan(Institute of Flow Chemistry ＆ Process Engineering, Changzhou University, Changzhou 213164, China;School of Pharmaceutical Engineering ＆ Life Science, Changzhou University, Changzhou 213164, China)
出处
《现代化工》
CAS
CSCD
北大核心
2018年第5期85-89,共5页
Modern Chemical Industry
关键词
微通道反应器
甲苯
液相氧化
苯甲醛
microchannel reactor
toluene
liquid phase oxidation
benzaldehyde
