摘要
目的观察杞菊地黄丸治疗老年单纯收缩期高血压(ISHE)的临床效果。方法将医院2016年1月-2017年5月收治的ISHE患者78例随机分为观察组和对照组各39例。对照组常规口服卡托普利治疗,观察组采取杞菊地黄丸治疗,对比2组患者接受治疗后的血压变化。结果 2组治疗前自测肱动脉血压和24 h动态血压比较差异无统计学意义(P>0.05);治疗后2组的SBP、24h SBP和PP均较治疗前明显下降,但观察组下降程度明显优于对照组,差异具有统计学意义(P<0.05);治疗后2组DBP和24h DBP虽较治疗前有下降趋势,但无差异统计学意义(P>0.05)。观察组患者的总有效率为97.44%明显高于对照组的61.54%,差异有统计学意义(P<0.05)。结论ISHE患者服用杞菊地黄丸后,不仅使收缩压得以改善,舒张压也得到了改善,其应用在老年ISHE的治疗中是具有临床价值的。
Objective To investigate the clinical effect of qijudihuang pill in the treatment of elderly patients with isolated systolic hypertension(ISHE）. Methods 78 patients with ISHE who were admitted to the hospital from January 2016 to May 2017 were randomly divided into observation group and control group with 39 cases each. Control group was treated with routine oral captopril,and observation group was treated with qijudihuang pill. Compared the clinical effects of blood pressure changes after treatment in both groups. Results There was no significant difference between two groups of self-tested radial arterial blood pressure and 24 hour ambulatory blood pressure before treatment(P〈0. 05）. After treatment,SBP,24 h SBP and PP in two groups were significantly lower than before treatment,but observation group decreased,the degree was significantly better than that of control group,and the difference was statistically significant(P〉0. 05）. After treatment,DBP and 24 h DBP in two groups had a decreasing trend compared with that before treatment,but there was no significant difference(P〉0. 05）.The total effective rate in observation group was 97. 44%,which was significantly higher than 61. 54% in control group,the difference was statistically significant(P〈0. 05）. Conclusion Patients taking qijudihuang pill,not only can improve the systolic blood pressure,diastolic blood pressure even improved,its application is of clinical value in the treatment of hypertension in elderly isolated systolic.
作者
苏庆侦
SU Qingzhen(Emergency Department, The Traditional Chinese Medicine Hospital of Yinan County, Shandong Province, Yinan 276300, Chin)
出处
《临床合理用药杂志》
2018年第13期17-18,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
杞菊地黄丸
老年
单纯收缩期高血压
Qijudihuang pill
Elderly
Isolated systolic hypertension
