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高良姜-陈皮组方对胃寒证模型大鼠的影响

Research on Rats Model Stomach-cold Syndrome Effects of Compatibility of Different Compatibility Proportion of Alpinia Officinarum Hance Dried Tangerine or Orange Peel
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摘要 目的:研究高良姜-陈皮组方对胃寒证大鼠的影响。方法:采用冰水浴+冰水与冰NaOH灌胃建立大鼠胃寒模型,根据给药后不同组别大鼠的进食、饮水、排便量和大鼠胃组织石蜡包埋HE染色检查胃组织病理结果,并采用ELISA法检测血清中的白介素2(IL-2)水平变化,比较高良姜-陈皮组方对大鼠胃寒证的影响。结果:与模型对照组对比,中、高剂量组别大鼠的进食量、饮水量、IL-2含量、病理组织检查结果都有显著性差异。结论:高良姜-陈皮组方具有缓解胃寒证的作用。 OBJETIVE: To investigate effects of compatibility of proportion of Alpinia officinarum Hance and dried tangerine or orange peel on rats model of stomach-cold syndrome. METHODS: Rats model of stomach-cold syndrome is made by using water bath + ice and ice NaOH gavage, according to the different groups including the food intake, drinking water, Observation of paraffin embedded HE staining section in rat gastric tissue, observing Checking the IL-2 level by ELISA method, To investigate effects of compatibility of different compatibility proportion of Alpinia officinarum Hance and dried tangerine or orange peel on rats model of stomach-cold syndrome by the methods. RESULT: The rats eating, drinking and the level of IL-2 and the model control in the prescription of medium and high dose group ratio have significant difference. So the prescription can alleviate the stomach-galangal peel syndrome effect.
作者 孙继燕 张鑫 杨全 程轩轩 唐晓敏 张春荣 周良云 潘利明 Sun Jiyan;Zhang Xin;Yang Quan;Cheng Xuanxuan;Tang Xiaomin;Zhang Chunrong;Zhou Liangyun;Pan Liming(School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Key Laboratory of State Administration of Traditional Chinese Medicine for Production & Development of Cantonese Medicinal Materials, Guangzhou 510006, China)
出处 《广东化工》 CAS 2018年第9期18-19,共2页 Guangdong Chemical Industry
关键词 胃寒证 高良姜-陈皮组方 IL-2 胃组织 stomach-cold syndrome compatibility proportion of Alpinia officinarum Hance and dried tangerine or orange peel IL-2 stomach tissue
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