摘要
[目的]观察聪耳通窍汤联合西药治疗突发性耳聋疗效。[方法]使用随机平行对照方法,将76例住院患者按抛硬币方法简单随机分两组。对照组38例地塞米松,10mg/d,静注;三磷酸腺苷40mg+辅酶A 100U+0.5%葡萄糖250mL,1次/d,静滴。治疗组38例聪耳通窍汤(牛膝15g,当归、生地各10g,赤芍、石菖蒲各9g,桃仁、红花、枳壳、柴胡、桔梗、川芎、香附各6g,甘草3g;耳鸣加麝香5g;眩晕加水蛭6g;眼震加黄芪6g;恶心呕吐加黄精、龟甲各5g,1剂/d),水煎200mL,早晚口服;西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、听力、眩晕、耳鸣、恶心呕吐、眼震、低切全血黏度、高切全血黏度、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈15例,显效10例,有效12例,无效1例,总有效率97.37%;对照组痊愈11例,显效9例,有效10例,无效8例,总有效率78.95%;治疗组疗效优于对照组(P<0.05)。低切全血黏度、高切全血黏度两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]聪耳通窍汤联合西药治疗突发性耳聋,疗效满意,无严重不良反应,值得推广。
[Objective] To observe the ear Tongqiao Conger decoction combined with western medicine therapy for sudden deafness.[Method] using random parallel control method, 76 cases of hospitalized patients by coin method were randomly divided into two groups. The control group of 38 cases of intravenous injection of dexamethasone, 10 mg/d, 40mg; adenosine triphosphate coenzyme A 100U 0.5% 250mL glucose, 1/d, intravenous drip. Treatment group 38 cases of ear Tongqiao conger decoction （Achyranthes 15g, angelica the students, 10g, red peony root, calamus 9g, peach kernel, safflower, Fructus aurantii, Radix Bupleuri, Platycodon grandiflorum, Rhizoma Chuanxiong, Rhizoma Cyperi, 6g, licorice 3g plus musk 5g; tinnitus; vertigo nystagmus with Huangqi plus leech 6g; 6g; nausea and vomiting with Huang Jing, the shell of 5g, 1/d）, water decoction agent 200mL, sooner or later oral; westernmedicinewiththecontrolgroup. Continuous treatment with 14d for 1 courses. Observation of clinical symptoms, hearing, dizziness, tinnitus, nausea and vomiting, nystagmus, low shear blood viscosity, high shear blood viscosity. The adverse reaction, to judge the curative effect of treatment of 1 courses. [Results] The treatment group 15 cases were cured, 10 cases markedly effective, 12 cases effective, 1 cases ineffective, the total efficiency of 97.37%; control group 11 cases were cured, 9 cases markedly effective, 10 cases effective, 8 cases ineffective, the total efficiency of 78.95%; the treatment group than the control group （P〈0.05） low shear whole blood. High viscosity, whole blood viscosity of two groups were improved （P〈0.05）, the treatment group was better than the control group （P〈0.05）. [Conclusion] Tongqiao Conger decoction combined with western medicine in the treatment of sudden deafness, satisfactory curative effect, no serious adverse reactions, worthy of promotion.
作者
薛向上
徐文利
XUE Xiangshang;XU Wenli(ENT Department, People＇s Hospital of Qinyang City, Qinyang 454550, Henan,Chin)
出处
《实用中医内科杂志》
2018年第4期31-33,共3页
Journal of Practical Traditional Chinese Internal Medicine
关键词
突发性耳聋
聪耳通窍汤
地塞米松
三磷酸腺苷
辅酶A
听力
眩晕
耳鸣
恶心呕吐
眼震
低切全血黏度
高切全血黏度
中药复方
中西医结合治疗
随机平行对照研究
sudden deafness
Tongqiao conger decoction（聪耳通窍汤）
dexamethasone
adenosine triphosphate
coenzyme A
listening
vertigo
tinnitus
nausea and vomiting
nystagmus
low shear blood viscosity
high blood viscosity
integrated traditional Chinese and western medicine therapy
randomized controlled study
