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血清铁蛋白、降钙素原和C反应蛋白在感染性疾病诊断中的临床意义 被引量:30

The diagnostic value of ferritin,procalcitonin (PCT) and C-reactive protein (CRP) on infections disease
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摘要 目的评价血清铁蛋白(SF)、降钙素原(PCT)和C反应蛋白(CRP)对感染性疾病的诊断价值。方法回顾分析2012年至2017年明确诊断为感染性疾病患者190例,其中细菌感染130例(细菌感染组),病毒感染60例(病毒感染组)。对细菌和病毒感染组SF、CRP、PCT测定值进行统计分析。结果 190例感染性疾病病例中,细菌感染组(68.4%)PCT、CRP、SF水平均高于病毒感染组(31.6%),差异有统计学意义。细菌感染组ROC曲线分析:CRP、PCT、SF曲线下面积(AUC)分别为0.797、0.803、0.883。结论在感染性疾病患者中,SF、CRP、PCT对鉴别细菌和病毒感染有价值。 Objective To evaluate the diagnostic value of ferritin, procalcitonin (PCT) and C-reactive protein (CRP) on infectious diseases. Methods A total of 190 patients with infectious diseases in our hospital from 2012 to 2017 were enrolled and analysed retrospectively. Among them, bacterial infection was found in 130 cases (bacterial infection group), and viral infection in 60 cases (viral infection group). Serum levels of erritin, CRP, PCT in 190 patients were deteceted for further statistical analysis. Results Among the 190 cases of infectious fever, serum levels of erritin, C RP, PCT in bacterial infection group were higher than that in the viral infection group, with significant difference. The receiver operating curve (ROC) curve analysis showed that area under curve (AUC) of CRP ,PCT ,ferritin were 0. 797,0. 803,0. 883. Conclusions The present study identified ferritin, PCT and CRP that should be considered in the differential diagnosis of infectious diseases, providing useful information for future diagnosis.
作者 王燕 付雪莹 胡岚 黄光伟 王鹤 王超 齐文杰 Wang Yan;Fu Xueying;Hu Lan;Huang Guangwei;Wang He;Wang Chao;Qi Wenjie(Department of infection, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China)
出处 《中国医师杂志》 CAS 2018年第5期661-663,共3页 Journal of Chinese Physician
基金 北京市科学技术委员会资助(2151100004015029)~~
关键词 传染病/诊断 铁蛋白质类/代谢 降钙素/代谢 C反应蛋白质/代谢 Communicable diseases/DI Ferritins/ME Calcitonin/ME C-reactive protein/ME
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