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阿奇霉素治疗小儿支原体肺炎的临床效果观察 被引量:4

Clinical efficacy of Azithromycin in the treatment of Mycoplasma pneumonia in children
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摘要 目的探讨阿奇霉素治疗31例小儿支原体肺炎的临床效果。方法选取2014年6月~2017年6月我院收治的小儿支原体肺炎患者62例,随机分为对照组(n=31)和观察组(n=31)。两组均给予对症治疗,在此基础上,对照组再给予红霉素治疗,观察组则给予阿奇霉素治疗。比较两组的发热时间、咳嗽时间、啰音持续时间、治疗总有效率和不良反应发生率等指标。结果 (1)观察组发热时间、咳嗽时间和啰音持续时间均短于对照组(P<0.05)。(2)观察组治疗总有效率为94.5%,显著高于对照组(70.9%)(P<0.05)。(3)观察组不良反应发生率为12.9%,显著低于对照组(35.4%),差异均有统计学意义(P<0.05)。结论对小儿支原体肺炎的治疗,阿奇霉素可有效改善患儿的临床症状、体征,治疗效果好,不良反应少,是一种理想的治疗药物。 Objective To investigate clinical efficacy of Azithromycin in the treatment of 31 cases of Mycoplasma pneumonia in children.Methods A total of 62 children with Mycoplasma pneumonia were collected from June 2014 to June2017 in our hospital and were randomly divided into control group(n=31) and observation group(n=31).The two groups were given symptomatic treatment.On the basis of treatment,the control group was treated with Erythromycin,while the observation group was treated with Azithromycin.The therapeutic effects of the two groups were compared.Results(1)The fever time,cough time and rale time in the observation group were shorter than those in the control group(P〈0.05).(2)The total effective rate of the observation group was 94.5%,which was significantly higher than 70.9% of the control group(P〈0.05).(3)The adverse reaction rate of the observation group was 12.9%,which was significantly lower than 35.4% of the control group,the differences were statistically significant(P〈0.05).Conclusion In the treatment of children with Mycoplasma pneumonia,Azithromycin can effectively improve the patient′s clinical symptoms and signs,treatment effect is good,and adverse reaction is less.It is an ideal treatment drug.
作者 欧齐 OU Qi(Department of Pediatrics,Maternal and Child Health Care Family Planning Service Center of Yunfu City,Guangdong Province,Yunfu 527300,Chin)
出处 《中国当代医药》 2018年第13期160-162,共3页 China Modern Medicine
关键词 小儿支原体肺炎 阿奇霉素 红霉素 临床效果 Mycoplasma pneumonia in children Azithromycin Erythromycin Clinical efficacy
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