摘要
目的探究食管癌术后吸入性肺炎合并急性呼吸窘迫综合征患者预后的高危因素。方法选取79例食管癌术后吸入性肺炎合并急性呼吸窘迫综合征患者为研究对象,将其中的存活率与死亡率进行统计,并将其中不同基本情况(性别、年龄、心率、呼吸及氧合指数)和疾病治疗情况(吻合口瘘、MODS发生情况、呼吸困难病程、手术方式及TNM分期)患者的死亡率与存活率进行比较,同时采用Logistic分析处理上述因素与此类患者预后的关系。结果 79例死亡29例(36.71%),其中不同性别患者的死亡率无显著性差异(P>0.05),而其他不同基本情况和疾病治疗情况患者的死亡率则存在显著性差异。经Logistic显示,年龄、心率、呼吸及氧合指数、吻合口瘘、MODS发生情况、呼吸困难病程、手术方式及TNM分期均是此类患者死亡的高危因素(P<0.05)。结论食管癌术后吸入性肺炎合并急性呼吸窘迫综合征患者的预后较差,且受多种高危因素影响,应根据其危险因素给予针对性干预。
Objective To analyze the prognostic high risk factors of patients with aspiration pneumonia complicated with acute respiratory distress syndrome after esophageal cancer operation. Methods 79 patients with aspiration pneumonia complicated with acute respiratory distress syndrome after esophageal cancer operation were selected,and the survival rate and mortality of the patients were analyzed,and the survival rate and mortality of patients with different basic situation（ gender,ages,heart rate,respiration and oxygenation index）,disease and treatment situation（ anastomotic leakage,MODS,dyspnea course,surgical modes and TNM stages） were compared,and the relationship between those factors and prognosis of theses patients were ananlyzed with Logistic analysis. Results The mortality of 79 patients with aspiration pneumonia complicated with acute respiratory distress syndrome after esophageal cancer operation was higher,and the mortality of patients with different gender had no significant difference,P 〉 0. 05,while the mortality of patients with other basic situation,disease and treatment situation had significant differences,and the Logisticanalysis showed those factors were all the high risk factors of these patients for death,all P 〈 0. 05. Conclusion The prognosis of of patients with aspiration pneumonia complicated with acute respiratory distress syndrome after esophageal cancer operation is worse,and the ages,heart rate,respiration,oxygenation index,anastomotic leakage,MODS,dyspnea course,surgical modes and TNM stages are all the high risk factors,so they should receive targeted intervention.
作者
虎琼华
HU Qionghua(The Second People＇s Hosphal of Chengdu, Chengdu, 610041)
出处
《实用癌症杂志》
2018年第6期914-916,共3页
The Practical Journal of Cancer
关键词
食管癌
手术
吸入性肺炎
急性呼吸窘迫综合征
预后
高危因素
Esophageal cancer
Operation
Aspiration pneumonia
Acute respiratory distress syndrome
Prognosis
High risk factors
