摘要
碳酸酐酶(carbonic anhydrase,CA)是一种Zn2+依赖金属酶,能高效催化CO2的水合反应。CA通过调节细胞内外的酸碱平衡、气体交换等生理过程,参与多种疾病的发生、发展。研究发现,CA与多种消化系统疾病的发生、发展有关,也是预测其肿瘤发生及评估预后的重要生物学标志物。
Carbonic anhydrase（CA） is a family of zinc metalloenzymes that efficiently catalyzes the hydration of carbon dioxide. CA, by regulating the cell inside and outside the acid-base balance, gas exchange and other physiological processes, is involved in the occurrence and development of a variety of diseases. The study found that CA is associated with the occurrence and development of a variety of digestive diseases and is an important biomarker for predicting the occurrence and prognosis of tumors.
作者
曹景莹
杨文宇
周宇
梁坚
CAO Jing-ying;YANG Wen-yu;ZHOU Yu;LIANG Jian.(Department of Gastroenterology, the Affiliated Hospital of Guangdong Medical University, Zhanjiang 524000, Guangdong, CHIN)
出处
《海南医学》
CAS
2018年第11期1568-1570,共3页
Hainan Medical Journal
关键词
碳酸酐酶
消化系统良性疾病
消化系统恶性疾病
Carbonic anhydrase （CA）
Digestive system benign disease
Digestive system malignant disease
