摘要
目的探讨系统化干预对减少口腔癌患者术后呼吸道感染效果,旨在为口腔癌患者术后呼吸道感染的防治提供理论依据。方法选取2013年2月—2016年6月金华市中心医院口腔科收治的166例口腔癌患者,按照随机数字表法分为干预组83例和对照组83例,2组患者均接受手术切除治疗,术后对照组采用常规治疗,干预组在常规治疗的基础上实施系统化干预,干预后14 d观察2组患者呼吸道感染率、感染持续时间及细菌培养情况。结果干预后,干预组呼吸道感染率为2.41%(2/83)、感染持续时间为(3.34±0.73)d,对照组呼吸道感染率为10.84%(9/83)、感染持续时间为(5.75±1.27)d,观察组呼吸道感染率和感染持续时间明显低于对照组(P<0.05);干预前,2组细菌半定量计数比较差异无统计学意义(P>0.05),干预后对照组细菌半定量计数较干预前无显著变化(P>0.05),干预后干预组细菌半定量计数较干预前明显降低(P<0.05),且干预组细菌半定量计数明显低于对照组(P<0.05)。结论系统化干预对减少口腔癌患者术后呼吸道感染效果显著,可抑制细菌繁殖,减少感染的发生,值得临床推广应用。
Objective To investigate the role of systematic intervention in reducing postoperative respiratory infection in patients with oral cancer, and provide a theoretical basis for the prevention and treatment of postoperative respiratory infections in patients with oral cancer. Methods A prospective research method was used to select a total of 166 patients with oral cancer admitted to the department of stomatology of Jinhua Central Hospital from February, 2013 to June, 2016, those patients were divided into intervention group （83 cases） and control group （83 cases） according to the random number table method. The patients of both groups received surgical resection, the control group received routine treatment and intervention group received systematic intervention on the basis of routine treatment. The respiratory tract infection rate, infection duration and bacterial culture were observed on d14 after the intervention. Results The respiratory infection rate in the intervention group was 2.41% and the duration of infection was （3.34 ± 0.73 ） days ; the respiratory infection rate in the control group was 10.84% and the infection duration was （5.75±1.27 ） days, the respiratory tract infection rate and infection duration of intervention group was significantly lower than that of the control group （ P 〈 0.05 ） ; Before the intervention, there was no significant difference in the semi-quantitative bacterial count between the two groups （ P 〉 0.05 ）. After the intervention, the semi-quantitative count of bacteria of the control group had no significant change when compared with that before the intervention （ P 〉 0.05 ）, the intervention group was significantly lower than that be- fore the intervention （P 〈 0.05 ）, and the intervention group was significantly lower than the control group （P 〈 0.05 ）. Conclusion The effect of systematic intervention on reducing postoperative respiratory infection in patients with oral cancer is significant. Systematic intervention can inhibit bacterial growth and significantly reduce infection, which is worthy of clinical application.
作者
章蕾
童熹
李国民
陈春晖
方旭
陈琨
李小芳
ZHANG Lei;TONG Xi;LI Guo-min(Department of Stomatology , Jinhua Municipal Central Hospital, Jinhua , Zhejiang 310000, China)
出处
《中华全科医学》
2018年第8期1290-1292,1328,共4页
Chinese Journal of General Practice
基金
浙江省医药卫生科技项目(2014ZHB014)
关键词
系统化干预
口腔癌
呼吸道感染
效果
Systematic intervention
Oral cancer
Respiratory tract infection
Effect
