摘要
IgG4相关性疾病（immunoglobulin G4-related disease,IgG4-RD）是一种全身系统性疾病,常伴有炎性假瘤的形成。IgG4-RD可导致单器官或者多器官受累。由于此疾病具有侵袭的特性,常被误诊为恶性肿瘤或慢性感染。IgG4-RD的发病机制尚不清楚,侵犯组织中以大量IgG4＋浆细胞浸润为特点,部分患者可伴有血清中IgG4浓度的增高。
Immunoglobulin G4-related disease is a systemic idiopathic inflammatory lesion.It is mainly characterized by infiltration of dense IgG4-positive plasma cells,typical storiform fibrosis,obliterative phlebitis and increased serum levels of IgG4.Patients with IgG4-related disease have frequently multiple organs involvement including structural damages of head and neck.But reports of temporal bone involvement in this kind of disease are rarely seen.This article reviews the recent progress in clinical research of lgG4-related disease in otology.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2018年第12期956-959,共4页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
