摘要
目的:分析双膦酸盐相关性颌骨坏死(BRONJ)的临床及CT表现,探讨CT对BRONJ的诊断价值。方法:搜集BRONJ患者5例,其中3例经手术病理证实,2例经临床及影像学证实,5例均有完整的临床及影像学资料,回顾性分析其临床及影像学表现特点。结果:5例BRONJ患者均有不同程度的颌骨硬化,4例位于下颌骨,1例位于上颌骨,骨质硬化均累及牙槽嵴及齿槽骨板。2例BRONJ患者颌骨硬化较广泛,导致邻近的下颌管狭窄。5例BRONJ患者同时伴有溶骨性骨质破坏。结论:BRONJ常伴颌骨骨质硬化,易累及牙槽嵴及齿槽骨板是其特征性表现,CT检查有助于早期、准确地诊断BRONJ,可为临床诊断、鉴别诊断和治疗提供可靠依据。
Objective：This study was performed to evaluate the clinical manifestations and imaging features of bisphosphonate-related osteonecrosis of the jaws（BRONJ）.Methods：Five cases of BRONJ were included in this study for retrospective analysis：3 were confirmed by pathology,2 by imaging and clinical data.All had complete clinical and imaging data.Results：Osteosclerosis in the jaws were found in all 5 cases,four were located at the mandible,one in the maxilla all invading the alveolar ridge and alveolar plate.Diffuse osteosclerosis were found in 2 cases with narrowed mandibular canal.Osteolytic destruction of the jaws was found in 5 cases.Conclusions：The characteristic imaging findings in BRONJ was osteosclerosis of the jaws which commonly involved the alveolar ridge and the alveolar plate.CT examinations play an important role on diagnosis of BRONJ,which can provide robust clues in the clinical diagnosis,differential diagnosis and treatment.
作者
谢新凤
杨万群
黄飚
周彩红
陈静勿
曾辉
XIE Xin-feng,YANG Wan-qun,HUANG Biao(Department of Radiology,Guangdong General Hospital,Guangdong Academy of Medical Sciences, Guangzhou 510080, Chin)
出处
《放射学实践》
北大核心
2018年第5期488-492,共5页
Radiologic Practice
关键词
二磷酸盐相关性下颌骨坏死
颌骨坏死
体层摄影术
X线计算机
Bisphosphonate- related osteonecrosis of the jaws
Osteonecrosis of the jaws
Tomography
X-ray computed
