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周围型肺癌CT表现和血清肿瘤标志物CEA的关系研究 被引量:6

Study on Relationship between CT Manifestations and Serum Tumor Marker CEA in Peripheral Lung Cancer
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摘要 目的探讨周围型肺癌CT表现和血清肿瘤标志物CEA的关系。方法选取于我院行胸部螺旋CT检查、血清CEA检测的80例周围型肺癌患者及同期我院50例健康体检者的临床资料,比较不同病理类型肺癌患者的CEA水平,并分析肺癌CT表现与CEA水平的关系。结果肺腺癌患者的CEA水平显著高于肺鳞癌、小细胞肺癌患者及健康体检者(P<0.05)。肺癌分叶征、空泡征、肿瘤直径>2 cm、增强值>20 Hu、纵膈淋巴结转移患者的CEA水平均高于无分叶征、无空泡征、肿瘤直径≤2 cm、增强值≤20 Hu、无纵膈淋巴结转移患者(P<0.05);肺癌毛玻璃征、毛刺征、钙化灶患者的CEA水平与无毛玻璃征、无毛刺征、无钙化灶患者比较差异均无统计学意义(P>0.05)。结论周围型肺癌患者的CEA水平较高,与分叶征、空泡征、肿瘤直径>2cm、增强值>20 Hu、纵膈淋巴结转移等CT表现具有一定关联。 Objective To explore the relationship between CT manifestations and serum tumor marker CEA in peripheral lung cancer. Methods The clinical data of 80 cases of patients with peripheral lung cancer undergoing chest spiral CT and serum CEA detection in our hospital and 50 healthy people with examination at the same period were selected. The CEA levels in patients with different pathological types of lung cancer were compared, and the relationship between CT manifestations and CEA levels in lung cancer was analyzed. Results The CEA level of patients with lung adenocarcinoma was significantly higher than those of patients with lung squamous carcinoma or small cell lung cancer, and also the healthy people with examination(P 〈0.05). The CEA levels of patients with lobulated sign,vacuole sign, tumor diameter 〉 2 cm, enhancement value 〉 20 Hu and mediastinal lymph node metastases were higher than those of patients with non-lobulated sign, non-vacuole sign, tumor diameter ≤2 cm, enhancement value ≤20 Hu and non-mediastinal lymph node metastases(P 〈0.05). The CEA levels of patients with ground-glass sign, spicule sign and calcification had no statistical difference with those of patients without ground-class sign, spicule sign and calcification(P 〉0.05). Conclusions Patients with peripheral lung cancer have higher CEA levels, which has certain relationship with the CT manifestations of lobulated sign, vacuole sign, tumor diameter 〉 2 cm, enhancement value〉 20 Hu and mediastinal lymph node metastasis.
作者 吴标 黄列彬 梁英林 李宗业 陈相猛 陈钦贤 WU Biao,HUANG Liebin,LIANG Yinglin,LI Zongye,CHEN Xiangmeng,CHEN Qinxian(Jiangmen Central Hospital,Jiangmen 529071, Chin)
机构地区 江门市中心医院
出处 《临床医学工程》 2018年第5期563-564,共2页 Clinical Medicine & Engineering
关键词 周围型肺癌 CT表现 CEA 关系 Peripheral lung cancer CT manifestation CEA Relationship
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