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甲硫氨酸对小鼠毛发生长和脏器指数的影响

Effects of methionine in dietary on hair growth and organ indexes in mice
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摘要 选择血缘和体重相近的昆明小白鼠80只,随机分成4组,分别以0.12%(对照组),0.80%,1.60%,2.40%的甲硫氨酸(Met)处理,每个处理5个重复、每个重复雄雌鼠各2只。在毛发退行期和休止期分别采集毛发纤维、心脏、肝脏、脾脏、肺脏、肾脏和胸腺等,用于测定毛发直径和长度及各脏器指数。结果表明:0.80%,1.60%,2.40%3种处理能显著降低退行期毛发直径(P〈0.05);但对休止期毛发直径无显著影响(P〉0.05);0.80%,1.60%2种处理能显著降低退行期和休止期毛发长度(P〈0.05),显著提高退行期脾指数、肺指数和肾指数(P〈0.05),但对心指数、胸腺指数均无显著影响(P〉0.05);1.60%Met处理能显著提高休止期肝指数和肾指数(P〈0.05),但对心指数、脾指数无显著影响(P〉0.05)。综上,0.80%,1.60%2种处理能显著降低小鼠毛发直径、长度,并能显著提高小鼠退行期脾指数、肺指数和肾指数。 The effects of methionine(Met)in dietary on hair growth and organs indexes were investigated.A total of 80 Kunming mice with a similar genetic background and weight were randomly divided into 0.12%(the control),0.80%,1.60%,and 2.40% Met treatments with five replicates per treatment,including two female and two male mice per treatment.The hair fibers,heart,liver,spleen,lungs,kidneys and thymus were collected in catagen and telogen,respectively.The results showed that hair diameters of mice were significantly decreased by adding 0.80%,1.60%and 2.40% Met to diet(P〈0.05)in catagen and telogen.The length of hair in catagen and telogen were significantly reduced by 0.80% and 1.60% Met supplement(P〈0.05),but no changes were observed in hair diameters of the mice among four groups(P〈0.05).Compared with 0.12% Met group,spleen,lung,and renal indexes of mice from 0.80% and1.60% Met groups were significantly improved(P〈0.05),but no significant effects of methionine were found on heart and thymus indexes(P〉0.05).Mice liver and renal indexes were significantly increased by 1.60% Met(P〈0.05),but no changes were observed in cardiac and spleen indexes(P〈0.05).In conclusion,the length and diameter of hair was significantly reduced,and spleen,lung and renal indexes were improved the by 0.80% and 1.60% Met in dietary.
作者 李晓凤 王昕 杨兵 张华琦 LI Xiao-feng;WANG Xin;YANG Bing;ZHANG Hua-qi(Tongren Polytechnic College, Tongren , Guizhou 554300, China;College of Animal Science and Technology, Northwest A & F University, Yangling , Shaanxi 712100, China)
出处 《食品与机械》 CSCD 北大核心 2018年第4期175-179,共5页 Food and Machinery
基金 铜仁市科技计划项目(编号:铜市科研[2016]17-4,[2017]47-91,[2017]-19) 铜仁职业技术学院科研项目(编号:铜职科研[2015]-1)
关键词 甲硫氨酸 毛发生长 脏器指数 小鼠 methionine hair growth organs index mice
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