摘要
经过30年的发展,中药色谱指纹图谱技术从学术探讨深入中药研发并应用到实践,推动了中药产业的技术革新与中药质量标准的进步。中药色谱指纹图谱相似度评价方法在这个过程中起到了决定性的作用。结合中药色谱指纹图谱30年发表文献的数量变化及研究趋势,把中药色谱指纹图谱相似度评价划分为3个阶段：即直观比较阶段（1988—1999年）、相似度评价起步阶段（2000—2009年）和相似度评价发展完善阶段（2010—2017年）。该文总结了中药色谱指纹图谱相似度评价方法30年研究进展并对未来发展方向进行了展望,以期推动中药色谱指纹图谱相似度评价方法走向成熟阶段。
Over the past 30 years,the chromatographic fingerprint technology of traditional Chinese medicine（ TCM） has been developed from academic discussion to application for the research and development of TCM which has promoted the technological innovation of Chinese medicine industry and the progress of quality standard of TCM. The similarity evaluation method of chromatographic fingerprint of TCM has played a key role in this process. According to the number of literature and research tendency in terms of the chromatographic fingerprint in the last 30 years,the chromatographic fingerprint evaluation could be divided into three stages： the direct comparison stage（ 1988—1999）,similarity evaluation stage（ 2000—2009） and the similarity evaluation development stage（ 2010—2017）. In this paper,the research progress of chromatographic fingerprints similarity evaluation of TCM in the last 30 years and its prospect were discussed,which may lead to a more mature stage for this method.
作者
邹纯才
鄢海燕
ZOU Chun-cai;YAN Hai-yan(Pharmacy School of Wannan Medical College, Wuhu 241002, China)
出处
《中国中药杂志》
CAS
CSCD
北大核心
2018年第10期1969-1977,共9页
China Journal of Chinese Materia Medica
基金
安徽高校省级自然科学研究重大项目(KJ2015ZD41,KJ2016SD60)
关键词
中药色谱指纹图谱
相似度评价方法
质量控制
chromatographic fingerprint of traditional Chinese medicine
similarity evaluation method
quality control
