摘要
宫颈癌是妊娠期妇女最常见的妇科肿瘤之一。妊娠期宫颈癌的治疗不仅需要考虑母体因素,还应考虑胎儿等因素。妊娠期诊断为宫颈癌的患者选择推迟到胎儿成熟后进行治疗给妇科医生带来了很大的挑战。新辅助化疗可以缩小肿瘤体积,似乎是妊娠期宫颈癌患者延长妊娠时间,使其获得存活新生儿的可行方法。新辅助化疗的出现为妊娠期宫颈癌患者的治疗提供了新的思路,但是妊娠期的新辅助化疗还需考虑胎儿因素,治疗过程相对复杂。本文就妊娠期新辅助化疗、妊娠期宫颈癌新辅助化疗药物选择、化疗时机及疗程安全性和疗效作一综述。
Cervical cancer is one of the most common gynecology tumor during pregnancy.Treatment of cervical cancer in pregnancy not only need to consider the maternal factors,but also take into accout the fetal and other factors.Treatment for cervical cancer patients,diagnosed during pregnancy,who desire to retain their pregnancy is a major challenge to gynecologist.Administration of neoadjuvant chemotherapy during pregnancy may decrease the occurence of premature delivery and it seems to be a feasible option to delay delivery until fetal survival.Here,we describe the potential to use neoadjuvant chemotherapy during pregnancy,the chemotherapeutics selection,the optional time and safety.
作者
陈雨柔
张蔚
吴寒舒
刘福林
吴婉蓉
伍克佳
CHEN Yurou;ZHANG Wei;WU Hanshu;LIU Fulin;WU Wanrong;WU Kejia(Dept. of Gynaecology and Obstetrics, Renmin Hospital of Wuhan University, Wuhan 430060 ,China;Dept. of Gynaecology and Obstetrics,Zhongnan Hospital of Wuhan University, Wuhan 430071 ,China)
出处
《武汉大学学报（医学版）》
CAS
2018年第4期531-535,共5页
Medical Journal of Wuhan University
关键词
宫颈癌
妊娠期
新辅助化疗
Cervical Cancer
Pregnancy
Neoadjuvant Chemotherapy
