摘要
目的探讨分析应用三联疗法治疗幽门螺杆菌(HP)相关的复发性口腔溃疡(ROU)的临床效果。方法选取2016年10月—2017年10月收治的HP相关的ROU患者100例纳入研究,随机分为观察组与对照组,各50例。观察组采用三联疗法联合西吡氯铵含漱液进行治疗,对照组采用西吡氯铵含漱液漱口治疗,两组治疗周期均为7 d。比较两组临床疗效及不良反应情况。结果观察组总有效率为98%高于对照组的66%,差异有统计学意义(P<0.05);两组不良反应比较差异无统计学意义(P>0.05)。结论基于三联疗法治疗ROU可以取得良好的临床效果,且不增加不良反应发生率。
Objective To explore the clinical effect of triple therapy on recurrent oral ulcer（ROU）associated with helicobacter pylori（HP）.Methods A total of 100 cases with HP related ROU selected from October 2016 to October 2017 were randomly divided into the observation group and the control group, 50 cases in each group. The observation group were treated with triple therapy combined with cetylpyridnium chloride gargle and the control group were treated with cetylpyridnium chloride gargle mouthwash treatment. The treatment cycle was 7 days. Clinical effects and adverse reactions between the two group were compared.Results The total effective rate of the observation group（98%） was higher than that of the control group（66%）, and the difference was significant（P〈0.05）.The difference of adverse reactions between the two groups was not significant（P〉0.05）.Conclusion Triple therapy based on ROU can achieve good clinical results without increasing the incidence of adverse reactions.
作者
薛国光
XUE Guoguang(Department of Stomatology, Gaotang People＇s Hospital Shandong 252800, Chin)
出处
《社区医学杂志》
2018年第12期7-8,共2页
Journal Of Community Medicine
