摘要
目的研究右美托咪定联合表面麻醉与瑞芬太尼联合表面麻醉在小儿支气管异物取出术中的效果对比分析。方法选择2015年2月至2016年12月在该院进行支气管异物取出的患儿84例,按照麻醉方法不同分为观察组和对照组。对照组使用瑞芬太尼联合表面麻醉,观察组使用右美托咪定联合表面麻醉,观察两组患儿不同时间点平均动脉压(MAP)、心率(HR)、血氧饱和度(SPO2)变化及术中不良反应发生情况。结果术中,观察组出现低氧血症、呼吸抑制等不良反应的患儿明显低于对照组,两组差异有统计学意义(P<0.05);拔管后20min,观察组MAP、HR值明显低于对照组,差异有统计学意义(P<0.05);在支气管镜置入后5min,观察组患儿SPO2较对照组明显升高,两组差异有统计学意义(P<0.05);术后,观察组患儿苏醒时间明显短于对照组,两组差异有统计学意义(P<0.05)。结论右美托咪定联合表面麻醉较瑞芬太尼联合表面麻醉更适合用于临床小儿支气管异物取出术,为临床小儿支气管异物取出术提供了更多的麻醉方法。
Objective To comparatively analyze the effects of dexmedetomidine combined with surface anesthesia and remifentanil combined with surface anesthesia in bronchial foreign body removal surgery in children.Methods A total of 84 children with bronchial foreign body in who received therapy from February 2015 to December 2016.Those patients were divided into the control group and the observation group according to different treatment methods.A total of 84 children with bronchial foreign body treated in the hospital from February 2015 to December 2016 were divided into the observation group and the control group according to the anesthesia methods.The control group was treated with remifentanil combined with surface anesthesia,and the observation group was treated with dexmedetomidine combined with surface anaesthesia,and the changes of mean arterial pressure（MAP）,heart rate（HR）,blood oxygen saturation（SPO2）and adverse reactions in two groups at different time points were observed.Results The number of children with hypoxemia and respiratory depression was significantly lower than that of the control group,and the difference was statistically significant（P〈0.05）.During the operation,the number of children with hypoxemia and respiratory depression in the observation group was significantly lower than that in the control group,and the difference was statistically significant（P〈0.05）.20 min after extubation,the values of MAP and HR in the observation group were significantly lower than those in the control group and the difference was statistically significant（P〈0.05）.5 min after the bronchoscopy,the SPO2 level of the observation group was significantly higher than that of the control group,and the difference was statistically significant（P〈0.05）.After the operation,the waking time of the children in the observation group was significantly shorter than that in the control group,and the difference was statistically significant（P〈0.05）.Conclusion Dexmedetomidine combined with surface anesthesia is more suitable for clinical pediatric bronchial foreign body removal surgery in comparison with remifentanil combined with surface anesthesia which provides an alternative way of anesthesia for clinical pediatric bronchial foreign body removal.
作者
王明全
吴爱玲
WANG Mingquan;WU Ailing(Department of Anesthesiology,the First People′s Hospital of Neijiang,Neijiang,Sichuan 641000, China)
出处
《检验医学与临床》
CAS
2018年第11期1593-1596,共4页
Laboratory Medicine and Clinic
关键词
右美托咪定
表面麻醉
瑞芬太尼
小儿支气管异物
dexmedetomidine
surface anesthesia
remifentanil
bronchial foreign body in children
