摘要
Peptide-based probes play prominent roles in biomedical research due to their promising properties such as high biocompatibility,fast excretion, favorable pharmacokinetics as well as easy and robust preparation. Considering the translation of imaging probes into clinical applications, peptide-based probes remain to be the most desirable and optimal candidates. This review summarized the development of peptide-based probes with promising imaging modalities and highlighted the successful applications for in vivo biomedical imaging.
Peptide-based probes play prominent roles in biomedical research due to their promising properties such as high biocompatibility,fast excretion, favorable pharmacokinetics as well as easy and robust preparation. Considering the translation of imaging probes into clinical applications, peptide-based probes remain to be the most desirable and optimal candidates. This review summarized the development of peptide-based probes with promising imaging modalities and highlighted the successful applications for in vivo biomedical imaging.
基金
partially supported by grants from the National Natural Science Foundation of China(NSFC Nos. 21708012,81773674, 81573383,21390402, 81725009, 21788102, 81425015)
111 Project (No. B17019)
NKR&DPC (No. 2016YFA00900)
NSFHP(Nos. 2017CFB151, 2017CFA024, 2017CFB711, 2016ACA126)
ABRPSTCS (No. SYG201521)
NSFJP (No. BK20160387)
Shenzhen Science and Technology Research Grant (No. JCYJ20170303170809222)
self-determined research funds of CCNU from the colleges, basic research and operation of MOE for the Central Universities (No. 23020205170469)
Wuhan Morning Light Plan of Youth Science and Technology (No. 201705304010321)
