摘要
目的讨论老年冠状动脉搭桥术后平均动脉压与急性肾损伤的关系。方法选择250例行体外循环下冠状动脉搭桥的老年患者,根据术后平均动脉压分为4组:66~70 mm Hg组、71~75 mm Hg组、76~80 mm Hg、≥81 mm Hg组,回顾性比较各组的术后6 h乳酸清除率、急性肾损伤发生率、住重症监护室(ICU)时间、30 d死亡率。结果 4组患者间术后急性肾损伤发生率及30 d死亡率比较,差异无统计学意义(P>0.05)。平均动脉压71~75 mm Hg组较其他3组患者的术后6 h乳酸清除率高、住ICU时间短,差异有统计学意义(P<0.05)。结论老年冠状动脉搭桥术后进一步提高高于65 mm Hg的平均动脉压并不能减少急性肾损伤的发生率。
Objective To discuss the relationship between postoperative mean arterial pressure and acute renal injury in elderly patients after coronary artery bypass grafting. Methods A total of 250 elderly patients undergoing coronary artery bypass grafting were divided into four groups according to the postoperative mean arterial pressure： 66-70 mm Hg group, 71-75 mm Hg group, 76-80 mm Hg group, and ≥ 81 mm Hg group. The 6-h lactic acid clearance rate, the incidence of acute renal injury, the length of ICU stay and the 30-d mortality were compared retrospectively among the groups. Results There was no significant difference in the incidence of acute renal injury or the 30-d mortality among the four groups（P〉0.05）. The 6-h lactic acid clearance rate was the highest and the length of ICU stay was the shortest in the 71-75 mm Hg group（P〈0.05）. Conclusions Increasing the postoperative mean arterial blood pressure which is higher than 65 mm Hg could not reduce the incidence of acute renal injury after coronary artery bypass grafting in the elderly.
作者
李涛
刘先日
尹培刚
段军
王书鹏
李刚
陈德生
Tao Li;Xian-ri Liu;Pei-gang Yin;Jun Duan;Shu-peng Wang;Gang Li;De-sheng Chen(Surgical Intensive Care Unit, China-Japan Friendship Hospital, Beijing 100029, China;Zhucheng People＇s Hospital, Zhucheng, Shandong 262200, China)
出处
《中国现代医学杂志》
CAS
2018年第16期64-66,共3页
China Journal of Modern Medicine
基金
北京市科技计划课题(No:Z131107002213038)
关键词
老年
冠状动脉搭桥术
术后平均动脉压
急性肾损伤
elderly
coronary artery bypass grafting
postoperative mean arterial pressure
acute renal injury
