摘要
目的探讨兰索拉唑治疗内镜息肉切除诱发胃溃疡4周与8周的疗效。方法选取2017年6月—2018年3月期间收治的行内镜息肉切除诱发胃溃疡的60例患者,利用随机数表法分为2组,各30例。对照组采用兰索拉唑治疗,连续治疗4周;观察组兰索拉唑服用方法及剂量与对照组相同,连续治疗时间为8周,对比2组临床疗效、溃疡愈合率及溃疡面积。结果观察组治疗总有效率较对照组高,差异有统计学意义(P<0.05);观察组溃疡愈合率较对照组高,差异有统计学意义(P<0.05)。治疗前,2组患者溃疡面积对比,差异无统计学意义(P>0.05);治疗后,2组患者溃疡面积均缩小,且观察组较对照组小,差异有统计学意义(P<0.05)。结论兰索拉唑治疗内镜息肉切除诱发胃溃疡8周可有效提升临床疗效,提高溃疡愈合率,缩小溃疡面积。
Objective To investigate the efficacy of lansoprazole in treatment of gastric ulcer induced by endoscopic polypectomy in 4 and 8 weeks.Methods 60 patients with gastric ulcer induced by endoscopic polypectomy in our hospital from June 2017 to March 2018 were selected,and they were divided into two groups by random number table,with 30 cases in each group.Control group was given lansoprazole for 4 weeks,while observation group was treated with same dose of lansoprazole for 8 weeks. The clinical efficacy,ulcer healing rate and ulcer area were compared between the two groups. Results The total effective rate of observation group was higher than that of control group（P〈0.05）.The ulcer healing rate of observation group was higher than that of control group（P〈0.05）.Before treatment,there was no statistical difference in the ulcer area between the two groups（P〉0.05）.After treatment,the ulcer area of two groups reduced,and observation group was smaller than control group（P〈0.05）.Conclusion Lansoprazole in treatment of gastric ulcer induced by endoscopic polypectomy for 8 weeks can increase clinical efficacy,promote the ulcer healing rate and reduce the ulcer area.
作者
李文英
刘佳
Li Wenying;Liu Jia(The People＇s Hospital ofWannian County,Shangrao,Jiangxi 334000;Shangrao Central Blood Station, Shangrao, Jiangxi 334000)
出处
《基层医学论坛》
2018年第17期2313-2314,共2页
The Medical Forum
基金
上饶市科技计划任务(20173CKJ22)
关键词
胃溃疡
内镜息肉切除
兰索拉唑
效果
Gastric ulcer Endoscopic polypectomy Lansoprazole Effect
