摘要
目的探讨全身麻醉对高糖高脂饲料诱导的2型糖尿病巴马小型猪空腹血糖的影响。方法巴马小型猪16头随机分为2组每组8头,对照组为正常饲料组,实验组为高糖高脂饲料诱导组。对16头巴马小型猪分别在全身麻醉前后测定空腹血糖,麻醉前后的血糖值进行组内、组间统计分析。结果两组小型猪在麻醉前后空腹血糖值差异显著,高糖高脂饲料组麻醉后空腹血糖值升高与对照组差异极显著。结论全身麻醉后巴马小型猪空腹血糖值明显升高,高糖高脂诱导的巴马小型猪2型糖尿病动物模型空腹血糖升高更为显著。
Objective Investigating the effect of general anesthesia on fasting blood glucose in type 2 diabetic Bama miniature pigs induced by high glucose and high fat diet. Method Sixteen head of Bama miniature pigs were randomly divided into 2 groups,eight heads in each group,the control group was normal feed group,and the experimental group was feed by high glucose and high fat diet. Fasting blood glucose was measured before and after general anesthesia in sixteen Bama miniature pigs. The blood glucose values before and after anesthesia were statistically analyzed in the group and between groups. Result The difference of fasting blood glucose between the two groups was significant before and after the anesthesia,and the fasting blood glucose levels in the high fat and high fat diet group increased significantly compared with the control group. Conclusion After general anesthesia,the fasting blood glucose levels of Bama miniature pigs increased significantly,and the fasting blood glucose increased significantly in the type 2 diabetic induced by high glucose and high fat dietcompared with the control group.
作者
相磊
刘亚千
赵玉琼
牛苗苗
袁记方
贾云晓
陈华
XIANG Lei;LIU Yaqian;ZHAO Yuqiong;NIU Miaomiao;YUAN Jifang;JIA Yunxiao;CHEN Hua(Laboratory animal center of PLA general hospital, Beijing 100853, china)
出处
《实验动物科学》
2018年第3期70-73,共4页
Laboratory Animal Science
基金
军队实验动物专项(No.SYDW[2014]001)
关键词
巴马小型猪
空腹血糖
2型糖尿病
麻醉
Bama miniature pigs
fasting blood glucose
type 2 diabetic
anesthesia
