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老年急性梗阻性化脓性胆管炎中西医结合治疗效果 被引量:1

Effect of Integrated Traditional Chinese and Western Medicine on Acute Obstructive Suppurative Cholangitis in The Elderly
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摘要 目的:探讨老年急性梗阻性化脓性胆管炎中西医结合治疗的效果。方法:100例老年AOSC患者,按照随机数字的方法将患者分为对照组和观察组,每个组50例患者,对照组患者使用常规的经皮肝穿刺胆道引流治疗方案,观察组患者在对照组患者治疗方法的基础上,使用茵陈蒿汤,对治疗的效果进行比较。结果:在进行治疗前,两组患者的谷丙转氨酶,谷草转氨酶,总胆红素和直接胆红素数据差异不具有统计学意义(P〉0.05),进行治疗后,两组患者的四项数据均出现降低,与治疗前数据差异具有统计学意义(P〈0.05)。治疗后的数据比较,观察组的数据低于对照组,数据差异具有统计学意义(P〈0.05),两组患者入院后开始治疗到进行手术的时间间隔和住院时间的数据差异均具有统计学意义(P〈0.05),均为观察组低于对照组,对照组的治疗有效率为72.00%,治疗组的治疗有效率为90.00%,两组数据差异具有统计学意义(X2=5.263,P〈0.05),治疗组的治疗有效率显著高于对照组,从两组的治疗效果看,数据差异也具有统计学意义(Z=4.004,P〈0.05),治疗组的治疗效果显著优于对照组,两组患者各项不良反应发生率的数据差异均不具有统计学意义(P〉0.05)。结论:利用中西医结合的方法对急性梗阻性化脓性胆管炎老年患者进行治疗,可以显著改善患者的肝功能状况,提升治疗的效果,缩短患者的住院时间,并且没有增加不良反应发生的概率,值得在临床范围内进行推广。 Objective: To explore the effect of combination therapy of traditional Chinese and Western medicine on patients with acute obstructive suppurative cholangitis. Methods: 100 cases of elderly patients' AOSC data,according to the method of random numbers,were divided into control group and observation group,50 patients in each group. The control group was treated with conventional percutaneous transhepatic biliary drainage treatment and patients in the observation group used Yinchenhao Decoction. We compared the treatment effect. Results: In two groups before treatment,the differences of alanine aminotransferase,aspartate aminotransferase,total bilirubin and direct bilirubin data were not statistically significant( P 〉0. 05). After treatment,four items of the data in the two groups decreased,and the difference was statistically significant( P 〈0. 05). After treatment,the data of observation group was lower than that of control group,and the difference of the data was statistically significant( P 〈0. 05). The difference between the two groups after the onset of hospitalization,the interval of operation and the length of hospital stay were statistically significant( P 〈0. 05). Those were lower in the observation group than those in the control group. The effective rate in the control group was 72% and that of the treatment group was 90%,and the difference between the two groups was statistically significant( χ~2= 5. 263,P 〈0. 05). The treatment efficiency of the treatment group was significantly higher than that of the control group. Two groups' data difference was also statistically significant( z = 4. 004,P 〈0. 05). The treatment group was significantly better than the control group. The difference of the incidence of adverse reactions between the two groups was not statistically significant( P 〉0. 05). Conclusion: The method of combining traditional Chinese and Western medicine treatment of acute obstructive suppurative cholangitis in elderly patients can significantly improve the liver function and the therapeutic effect,shorten the hospitalization times,and do not increase the probability of occurrence of adverse reactions. It is worthy of promotion in the clinical range.
作者 周新锋 夏卿 李祥 ZHOU Xinfeng;XIA Qing;LI Xiang(Department of Hepatobiliary and Pancreatic Surgery, The Second Hospital of Ningbo, Ningbo 315000, Zhejiang,China)
出处 《中华中医药学刊》 CAS 北大核心 2018年第7期1664-1667,共4页 Chinese Archives of Traditional Chinese Medicine
基金 浙江省自然科学基金项目(Y2080096)
关键词 急性梗阻性化脓性胆管炎 细菌感染 结石 acute obstructive suppurative cholangieis bacterial infection calculi
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