摘要
目的:探讨经鼻高流量湿化治疗对大面积脑梗死合并呼吸衰竭患者气管插管率及病死率的影响。方法:回顾性分析我院重症监护室(ICU)收治的220例大面积脑梗死合并呼吸衰竭患者的临床资料。根据患者接受治疗方法分为对照组和治疗组,其中对照组患者115例,接受普通鼻导管吸氧治疗;治疗组患者105例,接受经鼻高流量湿化治疗。比较2组患者住院期间的气管插管率、入院至气管插管时间、ICU住院天数、入院后7d及30d病死率。结果:治疗组患者住院期间的气管插管率低于对照组患者(P<0.05);2组患者的入院至气管插管时间比较差异无统计学意义(P>0.05);治疗组患者的ICU住院时间长于对照组(P<0.05);治疗组患者7d病死率低于对照组(P<0.05);2组患者30d病死率比较差异无统计学意义(P>0.05)。结论:经鼻高流量湿化治疗可降低大面积脑梗死合并呼吸衰竭患者的气管插管率,降低7d病死率,并且可以减少体内CO2潴留。
Objective：To investigate the effects of high flow nasal humidification oxygen therapy in patients with massive cerebral infarction and respiratory failure.Method：We retrospectively analyzed 220 patients with massive cerebral infarction and respiratory failure who were admitted to the Intensive Care Unit（ICU）in our hospital.Patients divided into a control group and a treatment group according to the treatment method.115 patients in the control group were treated with ordinary nasal catheter oxygen,and 105 patients in the treatment group received the treatment of high flow nasal humidification oxygen.The tracheal intubation rate,admission to tracheal intubation time,ICU hospitalization days,and the mortality of 7 and 30 days after admission were compared between the two groups.Result：The tracheal intubation rate in the treatment group was lower than that in the control group（P〈0.05）.There was no significant difference during the time between admission and intubation between the two groups（P〉0.05）.The hospitalization time of the treatment group in ICU was longer than that in the control group（P〈0.05）.The 7-day-mortality rate in the treatment group was lower than that of the control group（P〈0.05）.There was no significant difference in mortality between the two groups in 30 days（P〉0.05）.Conclusion：Transnasal high flow humidification oxygen can reduce the tracheal intubation rate of patients with large area cerebral infarction and respiratory failure,reduce the 7-day-mortality,and reduce the retention of CO2 in the body.
作者
袁关利
刘银凤
张鑫宇
吕哲
刘洪伟
张重阳
YUAN Guanli;LIU Yinfeng;ZHANG Xinyu;LV Zhe;LIU Hongwei;ZHANG Chongyang(Department of Emergency, First Hospital of Qinhuangdao, Hebei, Qinhuangdao, 066000, Chin)
出处
《临床急诊杂志》
CAS
2018年第6期379-381,共3页
Journal of Clinical Emergency
关键词
经鼻高流量湿化治疗
脑梗死
呼吸衰竭
high flow humidification
cerebral infarction
respiratory failure
