摘要
目的:贫血与慢性心衰患者远期不良事件密切相关,但贫血对心衰早期的影响尚未明确,探讨贫血对首诊急性心力衰竭患者1年死亡率的影响。方法:纳入2012年1月-2016年9月在本院首次住院的500例急性心力衰竭老年患者,根据是否贫血分为贫血组(310例)与非贫血组(190例)。对所有患者进行为期1年的随访,通过Cox回归分析贫血与HF患者不良预后的关系。结果:贫血组住院时间明显大于非贫血组,差异有统计学意义(P<0.01)。贫血组30 d死亡率8.7%高于非贫血组3.7%,差异有统计学意义(X^2=4.694,P=0.030)。贫血组1年死亡发生率28.1%高于非贫血组18.4%,差异有统计学意义(X^2=5.939,P=0.016)。通过Cox回归分析,贫血是急性HF患者1年死亡率的风险因子[HR=1.778,95%CI(1.183,2.601),P<0.001]。结论:贫血是首次住院急性心力衰竭患者远期不良事件经济有效观察指标。
Objective：To discuss the effect of anemia on the mortality rate of patients with acute HF in one year after initial diagnosis since anemia is closely related to long-term adverse events of patients with chronic HF,but the influence of anemia on the early phase of HF is still uncertain.Method：A total of 500 elderly patients with acute HF in our hospital from January 2012 to September 2016 were selected in this research,and they were divided into anemia group and non-anemia group according to whether they suffered from anemia.A follow-up visit was paid to all patients for one year,and the relation between anemia and poor prognosis of HF patients was analyzed through Cox regression.Result：There was no statistical difference between anemia group and non-anemia group in hospital stays（P〈0.05）.The mortality rate in 30 days of anemia group（8.7%） was higher than that of nonanemia group（3.7%）,the difference was statistically significant（ χ2=4.694,P=0.030）.The mortality rate in one year of anemia group（28.1%）was higher than that of non-anemia group（18.4%）,the difference was statistically significant（χ2=5.939,P=0.016）.According to Cox regression analysis,anemia was the risk factor of mortality rate of patients in one year[HR=1.778,95%CI（1.183,2.601）,P〈0.001].Conclusion：Anemia is an economic and effective observation indicator for long-term adverse events of acute HF patients hospitalized for the first time.
作者
吴博华
谢爵隆
何航宇
WU Bohua;XIE Juelong;HE Hangyu(Huazhou People＇s Hospital,Huazhou 525100,China)
出处
《中国医学创新》
CAS
2018年第13期124-127,共4页
Medical Innovation of China
关键词
急性心力衰竭
慢性心力衰竭
贫血
死亡率
Acute heart failure
Chronic heart failure
Anemia
Mortality rate
