摘要
目的：系统评价自血穴位注射治疗慢性荨麻疹的疗效与安全性。方法：计算机检索Pub Med、VIP、CNKI和Wan Fang,查找自血穴位注射治疗慢性荨麻疹的随机对照试验,检索时限均从建库至2017年9月。由2名研究者按照纳入与排除标准独立进行文献筛选、资料提取和质量评价后,采用Rev Man 5.3软件进行Meta分析。结果：纳入14个RCT,共1051例患者。Meta分析结果显示,自血穴位注射治疗慢性荨麻疹的有效率和痊愈率优于常规非自血疗法,复发率低于常规非自血疗法。尚未见自血穴位注射严重不良反应报告。结论：本系统评价结果显示,与常规非自血疗法相比,自血穴位注射有更好的治愈率和有效率,且能降低随访的复发率。但由于纳入文献数量较少,质量较低,需要高质量的多中心大样本随机双盲对照试验对其疗效优势做进一步研究。
Objective：To evaluate the efficacy and safety of autohemotherapy for chronic urticaria. Methods：Randomized controlled trials were searched among Pub Med,VIP,CNKI and Wan Fang Date from the retrieval database to September 2017. Two investigators according to the inclusion and exclusion criteria carried our the literature screening,data extraction,and quality evaluation independently. Meta analysis was performed by using Review Manager 5.3 software. Results：A total of 14 RCT literature were included in the standard,involving 1051 patients. Meta analysis results showed that the effective rate and cure rate in autohemotherapy group was better than that in conventional treatment group,and the recurrence rate in autohemotherapy group was lower than that in conventional treatment group. In adverse reactions,no serious adverse reactions have been reported. Conclusion：The evaluation results show that compared with conventional treatment group,autohemotherapy has better cure rate and efficiency,and can reduce the recurrence rate. However,due to the relatively small number of included literatures and low quality,it is need more high-quality multi-center large sample randomized double-blind controlled trials to verify.
作者
李彩彩
王少军
LI Caicai;WANG Shaojun(Acupuncture and Moxibustion Hospital of China Academy of Chinese Medical Sciences, Beijing 100700, China)
出处
《辽宁中医药大学学报》
CAS
2018年第7期101-104,共4页
Journal of Liaoning University of Traditional Chinese Medicine
基金
国家自然科学基金面上项目(81373724)
中国中医科学院院级第十一批基本科研业务费自主选题院内联合创新专项项目(ZZ11-050)
