摘要
目的:对不同厂家川芎配方颗粒的质量进行分析。方法:根据《中华人民共和国药典》(2015年版)"颗粒剂"项下要求,对6个厂家的颗粒进行水分、粒度、溶化性、药物引湿性、装量、浸出物、含量和指纹图谱测定,考察其质量。结果:6个厂家样品水分、粒度、装量和溶化性均符合规定,但不同厂家样品的浸出物、含量和指纹图谱的差距较大。结论:不同厂家生产的川芎配方颗粒的质量存在较大差异,临床用药需加以注意。
OBJECTIVE： To analyze the quality of Chuanxiong rhizoma formula granules from different manufacturers. METHODS： According to the requirements of the Pharmacopoeia of the People＇s Republic of China（2015 edition）,the moisture,particle size,solvency,drug induced moisture,loading,extraction,content and fingerprints were measured on the particles of 6 manufacturers and the quality was examined. RESULTS： The moisture content,particle size,loading,and solvency of the 6 manufacturers were all in compliance with the regulations,yet the gaps between the extraction, contents and fingerprints of different manufacturers＇ samples were larger.CONCLUSIONS： The quality of Chuanxiong rhizoma formula granules produced by different manufacturers is quite different,which need to be attached more importance in clinic.
作者
张肖建
朱梅羿
常云凤
李雪丽
高晗
李军山
李振江
ZHANG Xiaojian;ZHU Meiyi;CHANG Yunfeng;LI Xueli;GAO Han;LI Junshan;LI Zhenjiang(Ministry of Technology,Shineway Pharmaceutical Group Ltd.,Hebei Shijiazhuang 051430,China;Traditional Chinese Medicine Formula Granule Engineering Technology Research Center of Hebei,Hebei Shijiazhuang 050200,China)
出处
《中国医院用药评价与分析》
2018年第6期736-738,742,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
基金
国家中医药管理局中医药科学技术研究专项课题(No.国中医药科2013X07)
河北省科技计划项目(No.16272510)
河北省重点研发计划项目(No.17272505D)
关键词
不同厂家
川芎
配方颗粒
质量
对比分析
Different manufacturers
Chuanxiong rhizoma
Formula granules
Quality
Comparative analysis
