摘要
目的探讨小柴胡汤加减治疗慢性肾小球肾炎患者对炎症及蛋白尿改善的效果。方法方便选取该院2016年9月—2017年9月接收的106例慢性肾小球肾炎患者作为研究对象,依据临床用药方案分成2组,对照组(51例)行常规治疗,实验组(55例)于此基础上行小柴胡汤加减治疗,比对2组治疗前后证候积分变化、炎症及蛋白尿改善情况。结果治疗后实验组证候积分(8.69±2.06)分比对照组显著更低,差异有统计学意义(t=11.175 7,P<0.05);治疗后实验组IL-4(42.25±20.45)pg/mL等炎症因子及Upro(1.30±0.74)g/24 h水平均显著优于对照组(t=3.525 2、2.712 6,P<0.05)。结论 CGN行小柴胡汤加减治疗可取得确切疗效,有效减轻患者肾炎及蛋白尿,可被临床推广、普及。
Objective To study the effect of modified xiaochaihu decoction treatment of patients with chronic glomerulonephritis on the improvement of inflammation and proteinuria. Methods 106 cases of patients with chronic glomerulonephritis admitted and treated in our hospital from September 2016 to September 2017 were convenient selected and divided into two groups according to the clinical mediation plans, the control group with 51 cases used the routine therapy,while the experimental group with 55 cases were treated with xiaochaihu decoction on the basis of the control group, and the syndrome score changes, and improvement of inflammation and proteinuria before and after treatment were compared.Results After treatment, the syndrome score in the experimental group was（8.69±2.06） marks, which was obviously lower than that in the control group,the difference was statistically significant（t=11.175 7,P〈0.05）; after treatment, the IL-4 and Upro in the experimental group were respectively（42.25 ±20.45）pg/mL and（1.30 ±0.74）g/24 h, which were obviously better than those in the control group,（t=3.525 2, 2.712 6,P〈0.05）. Conclusion The modified xiaochaihu decoction in treatment of CGN can obtain a definite curative effect, which can effectively relieve the nephritis and proteinuria, and it can be promoted in clinic.
作者
张晓艳
张雪琴
ZHA NG Xiao-yan;ZHA NG Xue-qin(Department of Nephrology,Affiliated Hospital of Shared University of Traditional Chinese Medicine,Taiyuan,Shared Province,030024 Chin)
出处
《中外医疗》
2018年第9期159-161,共3页
China & Foreign Medical Treatment
关键词
小柴胡汤加减
慢性肾小球肾炎
炎症
蛋白尿
Modified xiaoehaihu decoction
Chronic glomerulonephritis
Inflammation
Proteinuria
