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重组牛碱性成纤维细胞生长因子凝胶治疗外伤性鼓膜穿孔的疗效评价 被引量:2

Therapeutic Evaluation of Recombinant Bovine Basic Fibroblast Growth Factor Gel in the Treatment of Traumatic Tympanic Perforation
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摘要 目的探讨重组牛碱性成纤维细胞生长因子凝胶治疗外伤性鼓膜穿孔的临床效果。方法选择2015年2月-2017年4月本溪市红十字会医院收治的88例外伤性鼓膜穿孔患者,采用信封法分为观察组和对照组各44例。对照组采用传统干燥保守疗法,观察组使用重组牛碱性成纤维细胞生长因子凝胶治疗。结果治疗后4周、2个月及3个月鼓膜愈合情况,观察组均优于对照组,差异均具有统计学意义(P〈0.05)。结论对于外伤性鼓膜穿孔,可以考虑使用重组牛碱性成纤维细胞生长因子凝胶进行治疗,能够缩短愈合时间,更有利于患者的康复。 Objective To observe the clinical effect of recombinant bovine basic fibroblast growth factor gel in the treatment of traumatic tympanic perforation. Methods A total of 88 patients with traumatic tympanic perforation were selected in Benxi Red Cross Hospital from February 2015 to April 2017, and divided into the observation group(44 cases) and the control group(44 cases) by the envelope method. The control group was treated by traditional dry conservative therapy, and the observation group was treated by recombinant bovine basic fibroblast growth factor gel. Results After treatment, the healing rate of tympanic perforation in the observation group were significantly better than the control group at different time-point (4 weeks, two months, and three months). Conclusion It is recommended that the patients with traumatic tympanic perforation could adopt recombinant bovine basic fibroblast growth factor gel, which can shorten the time of healing and be more beneficial for recovery.
作者 姜伟 JIANG Wei(Department of ENT,Benxi Red Cross Hospital,Benxi 743403,Liaoning Province,Chin)
出处 《中国实用乡村医生杂志》 2018年第7期67-68,71,共3页 Chinese Practical Journal of Rural Doctor
关键词 鼓膜穿孔 外伤性 治疗 重组牛碱性成纤维细胞生长因子凝胶 疗效 Tympanic Perforation Traumatic Treatment Recombinant Bovine Basic Fibroblast Growth Factor Gel Effect
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