摘要
目的研究血清胱抑素C同型半胱氨酸和脂蛋白a联合诊断脑梗塞的临床价值。方法方便选择该院在2016年8月—2017年8月收治的50例脑梗塞患者作为实验组,选择同时期在该院体检的正常人员作为对照组,对两组患者的临床危险因素和相应的实验室检查指标进行全面的观察,并且对其进行对比和统计学分析。结果对照组的血清胱抑素C、同型半胱氨酸和脂蛋白a的水平分别为(0.91±0.22)mg/L、(7.91±2.05)μmol/L、(177.50±91.28)mg/L,实验组的血清胱抑素C、同型半胱氨酸和脂蛋白a的水平分别为(1.64±0.81)mg/L、(13.25±4.10)μmol/L、(282.25±184.25)mg/L,明显实验组血清胱抑素C、同型半胱氨酸及脂蛋白a的水平比对照组高,数据差异有统计学意义(t=5.632、8.254、4.925,P<0.05)。结论血清胱抑素C、同型半胱氨酸及脂蛋白a的水平升高属于脑梗塞疾病发病的主要危险因素,将三者应用到脑梗塞患者病情评估和治疗过程中具有重要的现实意义,其值得临床推广使用。
Objective To research the clinical value of serum cystatin C, homocysteine and lipoprotein a in diagnosis of cerebral infraction. Methods 50 cases of cerebral infraction patients admitted and treated in our hospital from August 2016 to August 2017 were convenient selected as the experimental group, while the normal staff for physical examination at the same period were selected as the control group, and the clinical risk factors and corresponding laboratory examination indicators were comprehensively observed, and compared. Results The serum cystatin C, homocysteine and lipoprotein a in the control group were obviously higher than those in the control group [（0.91 ±0.22）mg/L,（7.91 ±2.05）μmol/L,（177.50 ±91.28）mg/L vs（1.64±0.81）mg/L,（13.25±4.10）μmol/L,（282.25±184.25）mg/L], and the differences were statistically significant,（t=t=5.632, 8.254,4.925,P〈0.05）. Conclusion The serum cystatin C, homocysteine and lipoprotein a are the major risk factors,and the application of the three in the evaluation and treatment course of cerebral infraction is of important realistic significance, which is worth clinical promotion and application.
作者
孙前进
SUN Qian-jin(Department of Clinical Laboratory,Xuzhou Hospital of TCM,Xuzhou,Jiangsu Province,221000 China)
出处
《中外医疗》
2018年第11期41-43,共3页
China & Foreign Medical Treatment
关键词
血清胱抑素C
半胱氨酸
脂蛋白A
脑梗塞
Serum eystatin C
Homoeysteine
Lipoprotein a
Cerebral infraction
