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自拟活血涤痰汤联合胺碘酮片治疗心血不足型心悸临床疗效观察

Effects of Using Zini Huoxue Ditan Decoction Combined with Amiodarone in the Treatment of Palpitation Patients with Syndrome of Heart Blood Deficiency
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摘要 目的:观察自拟活血涤痰汤联合胺碘酮片治疗心血不足型心悸的临床疗效。方法:选取2016年2月~2017年12月我院收治的94例心血不足型心悸患者,采用随机数字表法分为观察组和对照组。对照组口服给予胺碘酮片治疗,观察组在对照组基础上另口服给予自拟活血涤痰汤治疗,2组患者治疗时间均为4周。治疗后,观察患者的治疗效果。治疗前后,比较2组患者中医证候积分(心悸、头昏目眩、唇甲色淡、易惊健忘及失眠多梦),比较治疗前后2组患者超声心电图指标(SDANN、SDNNindex、SDNN及r MSSD)。治疗期间,观察2组患者不良反应。结果:治疗后,观察组总有效率为91.5%(43/47),明显高于对照组的79.1%(34/47)(P<0.05)。治疗后,观察组心悸、头昏目眩、唇甲色淡、易惊健忘及失眠多梦评分均明显低于对照组(P<0.05),而SDANN、SDNNindex、SDNN及r MSSD水平则均明显高于对照组(P<0.05)。治疗期间,所有患者均未出现严重不良反应。结论:自拟活血涤痰汤联合胺碘酮片治疗心血不足型心悸疗效较好,且安全性较高,值得进行深入研究。 Objective: To investigate the effects of Zini Huoxue Ditan Decoction combined with amiodarone in the treatment of palpitation patients with syndrome of heart blood deficiency. Methods: 94 cases of palpitation patients with syndrome of heart blood deficiency treated in our hospital from February 2016 to December 2017 were randomly divided into observation group and controlled group. The controlled group was treated with amiodarone,while the observation group was treated by Zini Huoxue Ditan Decoction on the basis of the controlled group. After the treatment,the effects were compared in the 2 groups. Before and after treatment,the levels of traditional Chinese medicine syndrome scores( palpitation,dizziness,light color,absent-mindedness and insomnia) were observed in the patients,while ultrasonic index( SDANN,SDNNindex,SDNN and r MSSD) were detected in the2 groups. Results: After the treatment,the effective rate was 91. 5%( 43/47) in the observation group,significantly higher than79. 1%( 34/47) in the controlled group( P〈0. 05). After the treatment,the scores of palpitation,dizziness,light color,absent-mindedness and insomnia were significantly lower in the observation group than the controlled group( P〈0. 05),while SDANN,SDNNindex,SDNN and r MSSD levels were significantly higher in the observation group than the controlled group( P 0. 05).During the treatment,there were no serious adverse actions in patients. Conclusions: Using Zini Huoxue Ditan Decoction combined with amiodarone in the treatment of palpitation patients with syndrome of heart blood deficiency has good effect and worthy of next study.
作者 王俊义 WANG Junyi(Youxian District Hospital of the Third People's Hospital of Mianyang City(Mianyang Sichuan 621000,China)
出处 《四川中医》 2018年第7期131-134,共4页 Journal of Sichuan of Traditional Chinese Medicine
关键词 自拟活血涤痰汤 胺碘酮片 心血不足型 心悸 Zini Huoxue Ditan Decoction Amiodarone Palpitation Syndrome of heart blood deficiency
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