摘要
目的探讨阻塞性睡眠呼吸暂停综合征(OSAHS)与高血压的相关性及影响因素。方法选取2012年9月—2016年9月期间该院收治的75例OSAHS患者作为研究对象,患者入院后均测量呼吸暂停低通气指数(AHI)指标,根据指标水平分为甲(轻度)、乙(中度)、丙(重度)3组,每组25例,3组患者均于每日早8:00及晚22:00测量血压水平,比较3组患者的血压水平变化情况,并分析危险因素。结果将3组患者的08:00与22:00两个时间段血压水平进行比较发现,组间数据差异有统计学意义(P<0.05)。其中丙组患者的08:00与22:00收缩压分别为(140.1±10.63)、(137.67±11.55)mmHg,舒张压水平分别为(93.4±5.65)、(91.54±4.16)mmHg,均明显高于甲组(t=10.825、10.086、10.803、7.732),而丙组患者的08:00与22:00收缩压水平明显高于乙组,组间数据差异有统计学意义(t=5.984、5.215,P<0.05)。OSAHS合并高血压患者的体重指数、腹围、血糖、三酰甘油、总胆固醇、高密度脂蛋白、低密度脂蛋白水平分别为(28.9±4.2)kg/m^2、(104.7±8.2)cm、(5.7±0.4)mmol/L、(2.2±0.4)mmol/L、(5.4±0.7)mmol/L、(1.0±0.1)mmol/L、(3.1±0.7)mmol/L,与单纯OSAHS患者差异有统计学意义(t=4.412、9.033、3.504、3.102、4.302、3.001、4.001,P<0.05)。结论 OSAHS与高血压的发病具有一定的相关性,临床治疗过程中,需注重分析可能引发高血压的危险因素,并采取措施预防,以降低患者并发高血压的风险。
Objective This paper tries to investigate the effect of obstructive sleep apnea syndrome（OSAHS） and the correlation and influencing factors of hypertension. Methods 75 cases of OSAHS patients in this hospital from September 2012 to September 2016 were selected as the research object, all the patients were measured apnea hypopnea index（AHI） index, according to the index level were divided into group A（mild）, B（moderate）, C（severe） groups, 25 cases in each group, three groups of patients in the early 8：00 and late 22：00 daily measurement of blood pressure levels,changes in blood pressure levels in patients with the three groups, and to analyze the risk factors. Results compared three groups of patients at 8：00 and 22：00 two time period of blood pressure level, found that the data difference between groups was significant（P〈0.05）, with statistical significance, patients of group C were measured the blood pressure at 8：00 and 22：00 of（140.1±10.63）,（137.67±11.55）mmHg, diastolic blood pressure levels were（93.4±5.65）,（91.54±4.16）mmHg, were significantly higher than that in group A（t=10.825, 10.086, 10.803, 7.732）. The systolic blood pressure of group C at 8：00 and 22：00 was significantly higher than that of group B. There was significant difference in data between groups（t=5.984, 5.215, P〈0.05）. OSAHS in the patients with hypertension and body mass index, waist circumference, blood glucose, triglyceride, three total cholesterol, high density lipoprotein, low density lipoprotein levels were（28.9±4.2）kg/m^2,（104.7±8.2）cm,（5.7±0.4）mmol/L,（2.2±0.4）mmol/L,（5.4±0.7）mmol/L,（1.0±0.1）mmol/L,（3.1±0.7）mmol/L,and the difference of simple OSAHS patients obviously, the difference was statistically significant（t =4.412, 9.033,3.504, 3.102, 4.302, 3.001, 4.001, P〈0.05）. Conclusion OSAHS and the incidence of hypertension has some relevance,the clinical treatment process needs to pay attention to analyze the possible risk factors for hypertension and take measures to prevent those factors, in order to reduce the risk of patients with high blood pressure.
作者
周明远
ZHOU Ming-yuan(Department of Respiratory,Chuxiong People＇ s Hospital of Yunnan,Chuxiong,Yunnan Province,675000 Chin)
出处
《系统医学》
2018年第3期57-59,共3页
Systems Medicine
