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铝碳酸镁对幽门螺杆菌感染活动性胃溃疡患者组织学溃疡愈合质量的影响探析 被引量:4

Study on effects of Hydrotalcite on the quality of histological ulcer healing in patients with active gastric ulcer induced by helicobacter pylori
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摘要 目的:对幽门螺杆菌感染活动性胃溃疡患者应用铝碳酸镁进行合理治疗,观察该药对于患者组织学溃疡愈合质量的影响。方法:收治符合本次研究要求的幽门螺杆菌感染活动性胃溃疡患者86例,按照入院顺序将患者分为观察组和对照组,每组43例。应用三联法对对照组患者进行治疗,观察组患者以此为治疗基础,加用铝碳酸镁进行治疗,对两组患者的临床治疗效果进行对比。结果:治疗过程结束后,观察组患者临床治疗有效率(88.37%)明显优于对照组(69.77%)(P<0.05);观察组患者幽门螺杆菌根除率为69.77%,效果明显优于对照组的48.84%(P<0.05)。结论:对于幽门螺杆菌感染活动性胃溃疡应用铝碳酸镁进行治疗疗效显著,能极大的提升治疗有效率和治疗安全性,具有良好的幽门螺杆菌根除效果。 Objective: To treat the active gastric ulcer patients induced by Helicobacter pylori infection with Hydrotalcite,and to observe its effects of on the healing quality of the patients. Methods: 86 cases of H.pylori-infected patients with active gastric ulcer,who met the requirements of this study,were enrolled. These patients were divided into observation group and control group according to the admission order,43 cases in each group. All the patients were treated with the triple therapy. Besides,the observation group was given Hydrotalcite. The clinical effects of the two groups were compared. Results: The effective rate in the observation group( 88.37%) was significantly better than that in the control group( 69.77%) after the treatment was completed( P〈0.05). The efficacy of H.pylori eradication in the observation group( 69. 77%) was significantly better than that of the control group( 48. 84%)( P〈0. 05).Conclusions: Hydrotalcite in the treatment of the patients with active gastric ulcer caused by Helicobacter pylori has significant curative effects,can greatly improve the treatment efficiency and treatment safety,and has good effects of eradication of Helicobacter pylori.
作者 徐晓霞 王晓晨 包玉双 李春明 XU Xiaoxia;WANG Xiaochen;BAOYushuang;LI Chunming(Deparment of Integrated Internal Medicine,Second Affiliated Hospital of Jiamusi University,Jiamusi Heilongjimlg 154002,China;Department of Anorectal Diseases,Jiamusi Central Hospital)
出处 《中国民康医学》 2018年第9期13-15,共3页 Medical Journal of Chinese People’s Health
关键词 铝碳酸镁 幽门螺杆菌 活动性胃溃疡 Hydrotalcite Helicobacter pylori Active gastric ulcer
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