期刊文献+

血清TgAb、TPOAb检测联合^(99m)TcO_4^-甲状腺静态显像对桥本甲状腺炎的诊断价值 被引量:6

下载PDF
导出
摘要 目的探讨血清TgAb、TPOAb检测联合^(99m)TcO_4^-甲状腺静态显像对桥本甲状腺炎(HT)的诊断价值。方法选取62例HT患者,选取30例健康成人为对照组。两组人员均进行甲状腺静态显像、电化学发光法测定血清游离甲状腺激素(FT_3、FT_4),促甲状腺激素(TSH),甲状腺球蛋白抗体(TgAb)及甲状腺过氧化物酶抗体(TPOAb),将两组结果进行比较分析。结果 62例HT患者中TgAb阳性58例(阳性率93.5%),TPOAb阳性48例(阳性率77.4%),30例正常对照组中TgAb增高1例,二者间差异有统计学意义;甲状腺静态显像HT患者中呈放射性摄取增高者29例(占46.8%),放射性摄取正常者22例(占35.5%),放射性摄取减低者11例(占17.7%),对照组中甲状腺静态显像均为放射性摄取正常,二者间差异有统计学意义。结论 TgAb与TPOAb在HT中阳性率较高,与正常对照组比较具有统计学意义,可作为该疾病的诊断依据;HT患者甲状腺摄取功能在不同激素水平间表现出复杂特点,甲状腺静态显像在HT诊断中有一定价值。
出处 《中国医药指南》 2018年第11期80-81,共2页 Guide of China Medicine
  • 相关文献

参考文献2

二级参考文献28

  • 1余英教,朱立英,朱德祥.桥本病115例临床分析[J].天津医药,1995,23(7):432-433. 被引量:3
  • 2冷希圣 黄萃庭.甲状腺炎症性疾病[J].普外临床,1988,6:364-364.
  • 3Guillen C,Prieto A,Alvarez-Escola C,et al.Abnormal functional behavior of peripheral blood mononuclear cells from Hashimoto's disease patients:immunomodulatory effects of cyclosporin A[J].Immunopharmacol Immunotoxicol,1999,21(1):15.
  • 4Iitaka M,Miura S,Yamanaka K,et al.Increased serum vascular endothelial growth factor levels and intrathyroidal vascular area in patients with Graves' disease and Hashimoto's thyroiditis[J].J Clin Endocrinol Metab,1998,83(11):3809.
  • 5Hegedus L,Hansen JM,Feldt-Rasmussen U,et al.Influence of thyroxine treatment on thyroid size and anti-thyroid peroxidase antibodies in Hashimoto's thyroiditis[J].Clin Endocrinol(Oxf),1991,35(3):235.
  • 6Kikuchi T,Yamaguchi Y,Kobayashi T,et al.Studies in thyroid volume during thyroid hormone therapy in patients with Hashimoto's thyroiditis.In Nagataki S,Mori T,Torizuka K eds.80 years of Hashimoto disease[M].Amsterdam:Elsevier Science,1993.201.
  • 7Rieu M,Richard A,Rosilio M,et al.Effects of thyroid status on thyroid autoimmunity expression in euthyroid and hypothyroid patients with Hashimoto's thyroiditis[J].Clin Endocrinol(Oxf),1994,40(4):529.
  • 8Dayan CM,Daniels GH.Chronic autoimmune thyroiditis[J].New Engl J Med,1996,335(2):99.
  • 9Crile GJ. FACS Cleveland Ohio struma lymphomatosa and carcino-ma of the thyroid[J].Surg Gynecol Obstet,1978,147(3):350.
  • 10Clark OH,Greenspan FS,Dunphy JE.Hashimoto's thyroiditis and thyroid cancer:indications for operation[J].Am J Surg,1980,140(1):65.

共引文献11

同被引文献30

引证文献6

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部