摘要
目的了解兰州市城关区居民碘营养状况和甲状腺结节的流行病学特征及影响因素。方法采用分层整群抽样的方法对兰州市城关区6个社区进行横断面调查,进行甲状腺超声检查、甲状腺功能检测及尿碘检测。结果甲状腺结节的患病率为21.0%,男、女分别为17.2%、25.2%,女性高于男性(P<0.05)。60岁之前患者人群以单发和直径<1.0cm的结节为主,60岁之后以多发和直径≥1.0cm的结节为主。甲状腺结节患者的甲状腺功能多为正常(81.6%),且二者无关联(P>0.05)。兰州地区人群尿碘中位数为205.4μg/L,高于国内其他地区,女性高于男性(P<0.05),尿碘水平随着年龄升高而逐渐降低(P<0.05)。年龄是甲状腺结节发生与发展的重要影响因素。结论兰州地区的尿碘水平较高;年龄与性别均与甲状腺结节的发生发展有关。
Objective To understand the iodine nutritional status in Chengguan District of Lanzhou, and the epidemiological characteristics and influencing factors of thyroid nodules.Methods Stratified cluster sampling was used to conduct a cross-sectional survey on six communities. Thyroid ultrasound, thyroid function and urine iodine were tested.Results The prevalence rate of thyroid nodules was 21.0% as a whole, with that of the men being, 17.2% and that of women being. Obviously, the prevalence rate of. women was higher than men （ P 〈 0.05 ）.The majority of patients under 60 years had single nodules less than 1.0 cm. Patients over 60 years had multiple thyroid nodules with the diameter greater than or equal to 1.0 cm. Thyroid function in patients with thyroid nodules was normal （ 81.6% ）, and there was no association between thyroid nodules and thyroid function（ P 〉 0.05 ）. The median urinary iodine level in Lanzhou area was 205.4 μg/L, higher than that in other areas of China, and significantly higher in women than men （ P 〈 0.05 ）. The urine iodine level decreased with age （ P 〈 0.05 ）. Age is an important factor affecting the occurrence and development of thyroid nodules.Conclusion The level of urine iodine is high in Lanzhou area. Both age and sex are related to the occurrence and development of thyroid nodules.
作者
曹冲
傅松波
汤旭磊
刘靖芳
马丽华
孙蔚明
牛滢
井高静
赵楠
牛强龙
杨芳
李玉娟
乌丹
郭慧萍
王斌莉
宋佩
滕卫平
单忠艳
Cao Chong 1, Fu Songbo 1, Tang Xulei 1, Liu Jingfang 1, Ma Lihua 1, Sun Weiming 1,Niu Ying 1, Jing Gaojing 1, Zhao Nan 1, Niu Qianglong 1, Yang Fang 1, Li Yujuan 1,Wu Dan 1, Guo Huiping 1, Wang Bingli 1, Song Pei 1, Teng Weiping 2, Shan Zhongyan 21(Department of Endocrinology, the First Hospital of Lanzhou University, Lanzhou 730000, China;2. Department of Endocrinology, the First Affiliated Hospital of China Medical University,Shenyang 101100, China)
出处
《临床荟萃》
CAS
2018年第7期587-590,共4页
Clinical Focus
基金
国家卫计委公益性行业科研专项(201402005)
兰州市城关区科技计划项目(2014-7-4)
兰州大学2017年大学生创新创业项目行动计划(20171073001237)
